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A comprehensive analysis of candidate genes in familial pancreatic cancer families reveals a high frequency of potentially pathogenic germline variants.
Early induction of senescence and immortalization in PGC-1α-deficient mouse embryonic fibroblasts.
Increased dosage of Ink4/Arf protects against glucose intolerance and insulin resistance associated with aging
Increased gene dosage of the Ink4/Arf locus does not attenuate atherosclerosis development in hypercholesterolaemic mice
Induction of DNA double-strand breaks and cellular senescence by human respiratory syncytial virus
Macrophages, inflammation, and tumor suppressors: ARF, a new player in the game