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Now showing items 1-14 of 14
A kinase-deficient NTRK2 splice variant predominates in glioma and amplifies several oncogenic signaling pathways.
ChiPPI: a novel method for mapping chimeric protein-protein interactions uncovers selection principles of protein fusion events in cancer
Development Refractoriness of MLL-Rearranged Human B Cell Acute Leukemias to Reprogramming into Pluripotency
Efficient Recreation of t(11;22) EWSR1-FLI1+ in Human Stem Cells Using CRISPR/Cas9
EWS-FLI1 confers exquisite sensitivity to NAMPT inhibition in Ewing sarcoma cells
EWS-FLI1 impairs aryl hydrocarbon receptor activation by blocking tryptophan breakdown via the kynurenine pathway.
EWS-FLI1-mediated suppression of the RAS-antagonist Sprouty 1 (SPRY1) confers aggressiveness to Ewing sarcoma
Genome-wide association study identifies multiple new loci associated with Ewing sarcoma susceptibility
Hippo pathway effectors YAP1/TAZ induce an EWS-FLI1-opposing gene signature and associate with disease progression in Ewing sarcoma.
In vivo CRISPR/Cas9 targeting of fusion oncogenes for selective elimination of cancer cells.
Lysyl oxidase is downregulated by the EWS/FLI1 oncoprotein and its propeptide domain displays tumor supressor activities in Ewing sarcoma cells
Systems analysis identifies melanoma-enriched pro-oncogenic networks controlled by the RNA binding protein CELF1
The role of miR-17-92 in the miRegulatory landscape of Ewing sarcoma
Uncovering suitable reference proteins for expression studies in human adipose tissue with relevance to obesity