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A Chemical Screen Identifies Compounds Capable of Selecting for Haploidy in Mammalian Cells
A synthetic lethal interaction between APC/C and topoisomerase poisons uncovered by proteomic screens.
Activation of the endomitotic spindle assembly checkpoint and thrombocytopenia in Plk1-deficient mice.
An E2F7-dependent transcriptional program modulates DNA damage repair and genomic stability
Aurora A controls CD8+ T cell cytotoxic activity and antiviral response
Aurora A drives early signalling and vesicle dynamics during T-cell activation
Biochemical analyses reveal amino acid residues critical for cell cycle-dependent phosphorylation of human Cdc14A phosphatase by cyclin-dependent kinase 1
Detection of novel fusion-transcripts by RNA-Seq in T-cell lymphoblastic lymphoma
E2F7 regulates transcription and maturation of multiple microRNAs to restrain cell proliferation
Functional reprogramming of polyploidization in megakaryocytes.
Keeping Order in Anaphase.
Plk1 overexpression induces chromosomal instability and suppresses tumor development
Plk1 regulates contraction of postmitotic smooth muscle cells and is required for vascular homeostasis
PTEN mediates Notch-dependent stalk cell arrest in angiogenesis
RNA-Seq reveals the existence of a CDKN1C-E2F1-TP53 axis that is altered in human T-cell lymphoblastic lymphomas
The anaphase promoting complex impacts repair choice by protecting ubiquitin signalling at DNA damage sites
The cell proliferation antigen Ki-67 organises heterochromatin
Thrombocytopenia-associated mutations in Ser/Thr kinase MASTL deregulate actin cytoskeleton dynamics in platelets