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A kinase-deficient NTRK2 splice variant predominates in glioma and amplifies several oncogenic signaling pathways.
EGFR feedback-inhibition by Ran-binding protein 6 is disrupted in cancer
MGMT genomic rearrangements contribute to chemotherapy resistance in gliomas.
Somatic genome editing with the RCAS-TVA-CRISPR-Cas9 system for precision tumor modeling