#term ID	term description	observed gene count	background gene count	strength	signal	false discovery rate	matching proteins in your network (IDs)	matching proteins in your network (labels)
GO:0006956	Complement activation	18	60	1.83	5.39	1.57e-22	9606.ENSP00000223642,9606.ENSP00000263408,9606.ENSP00000291744,9606.ENSP00000296280,9606.ENSP00000299367,9606.ENSP00000314299,9606.ENSP00000315130,9606.ENSP00000322061,9606.ENSP00000354458,9606.ENSP00000356037,9606.ENSP00000360281,9606.ENSP00000363079,9606.ENSP00000363770,9606.ENSP00000378131,9606.ENSP00000385035,9606.ENSP00000396688,9606.ENSP00000415941,9606.ENSP00000416561	C5,C9,FCN2,MASP1,C2,CFHR1,CLU,C7,C8A,C4BPA,C8B,MBL2,C1QC,CFI,C1S,C4A,C4B,CFB
GO:0006959	Humoral immune response	25	268	1.32	3.62	9.72e-22	9606.ENSP00000223642,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000261267,9606.ENSP00000263408,9606.ENSP00000291744,9606.ENSP00000296280,9606.ENSP00000299367,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000314299,9606.ENSP00000315130,9606.ENSP00000322061,9606.ENSP00000354458,9606.ENSP00000356037,9606.ENSP00000360281,9606.ENSP00000363079,9606.ENSP00000363770,9606.ENSP00000378131,9606.ENSP00000385035,9606.ENSP00000396688,9606.ENSP00000415941,9606.ENSP00000416561,9606.ENSP00000440066,9606.ENSP00000493985	C5,LTF,HRG,LYZ,C9,FCN2,MASP1,C2,FGB,F2,CFHR1,CLU,C7,C8A,C4BPA,C8B,MBL2,C1QC,CFI,C1S,C4A,C4B,CFB,JCHAIN,KNG1
GO:0006952	Defense response	42	1394	0.83	1.86	2.13e-21	9606.ENSP00000217407,9606.ENSP00000223642,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000253354,9606.ENSP00000255030,9606.ENSP00000255040,9606.ENSP00000261267,9606.ENSP00000262919,9606.ENSP00000263408,9606.ENSP00000264690,9606.ENSP00000265983,9606.ENSP00000266041,9606.ENSP00000273784,9606.ENSP00000278222,9606.ENSP00000291744,9606.ENSP00000292609,9606.ENSP00000296280,9606.ENSP00000299367,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000314299,9606.ENSP00000315130,9606.ENSP00000322061,9606.ENSP00000346839,9606.ENSP00000350425,9606.ENSP00000354458,9606.ENSP00000356037,9606.ENSP00000357156,9606.ENSP00000360281,9606.ENSP00000362924,9606.ENSP00000363079,9606.ENSP00000363770,9606.ENSP00000366109,9606.ENSP00000378131,9606.ENSP00000385035,9606.ENSP00000396688,9606.ENSP00000415941,9606.ENSP00000416561,9606.ENSP00000440066,9606.ENSP00000450540,9606.ENSP00000493985	LBP,C5,LTF,HRG,BPIFB1,CRP,APCS,LYZ,ATRN,C9,KLKB1,HPX,ITIH4,AHSG,SAA4,FCN2,PGLYRP2,MASP1,C2,FGB,F2,CFHR1,CLU,C7,FN1,APOA4,C8A,C4BPA,CD5L,C8B,GSN,MBL2,C1QC,ANXA1,CFI,C1S,C4A,C4B,CFB,JCHAIN,SERPINA3,KNG1
GO:0051346	Negative regulation of hydrolase activity	26	354	1.22	3.14	1.38e-20	9606.ENSP00000215727,9606.ENSP00000223642,9606.ENSP00000226218,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000254722,9606.ENSP00000255040,9606.ENSP00000263598,9606.ENSP00000265132,9606.ENSP00000266041,9606.ENSP00000273283,9606.ENSP00000273784,9606.ENSP00000329374,9606.ENSP00000333203,9606.ENSP00000342850,9606.ENSP00000343445,9606.ENSP00000351190,9606.ENSP00000355627,9606.ENSP00000366109,9606.ENSP00000377783,9606.ENSP00000396688,9606.ENSP00000415769,9606.ENSP00000415941,9606.ENSP00000450540,9606.ENSP00000465356,9606.ENSP00000493985	SERPIND1,C5,VTN,LTF,HRG,SERPINF1,APCS,LCN1,AMBP,ITIH4,ITIH1,AHSG,SERPINA7,SERPINA5,SERPINA6,SERPINB4,ITIH2,AGT,ANXA1,PROS1,C4A,ITIH3,C4B,SERPINA3,APOC1,KNG1
GO:0010951	Negative regulation of endopeptidase activity	23	240	1.34	3.52	2.49e-20	9606.ENSP00000215727,9606.ENSP00000223642,9606.ENSP00000226218,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000254722,9606.ENSP00000263598,9606.ENSP00000265132,9606.ENSP00000266041,9606.ENSP00000273283,9606.ENSP00000273784,9606.ENSP00000329374,9606.ENSP00000333203,9606.ENSP00000342850,9606.ENSP00000343445,9606.ENSP00000351190,9606.ENSP00000355627,9606.ENSP00000377783,9606.ENSP00000396688,9606.ENSP00000415769,9606.ENSP00000415941,9606.ENSP00000450540,9606.ENSP00000493985	SERPIND1,C5,VTN,LTF,HRG,SERPINF1,LCN1,AMBP,ITIH4,ITIH1,AHSG,SERPINA7,SERPINA5,SERPINA6,SERPINB4,ITIH2,AGT,PROS1,C4A,ITIH3,C4B,SERPINA3,KNG1
GO:0045861	Negative regulation of proteolysis	25	339	1.22	3.1	6.26e-20	9606.ENSP00000181383,9606.ENSP00000215727,9606.ENSP00000223642,9606.ENSP00000226218,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000254722,9606.ENSP00000263598,9606.ENSP00000265132,9606.ENSP00000266041,9606.ENSP00000273283,9606.ENSP00000273784,9606.ENSP00000308541,9606.ENSP00000329374,9606.ENSP00000333203,9606.ENSP00000342850,9606.ENSP00000343445,9606.ENSP00000351190,9606.ENSP00000355627,9606.ENSP00000377783,9606.ENSP00000396688,9606.ENSP00000415769,9606.ENSP00000415941,9606.ENSP00000450540,9606.ENSP00000493985	CPB2,SERPIND1,C5,VTN,LTF,HRG,SERPINF1,LCN1,AMBP,ITIH4,ITIH1,AHSG,F2,SERPINA7,SERPINA5,SERPINA6,SERPINB4,ITIH2,AGT,PROS1,C4A,ITIH3,C4B,SERPINA3,KNG1
GO:0030162	Regulation of proteolysis	31	739	0.98	2.21	9.77e-19	9606.ENSP00000181383,9606.ENSP00000215727,9606.ENSP00000223642,9606.ENSP00000226218,9606.ENSP00000230036,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000252486,9606.ENSP00000254722,9606.ENSP00000263598,9606.ENSP00000264690,9606.ENSP00000265132,9606.ENSP00000266041,9606.ENSP00000273283,9606.ENSP00000273784,9606.ENSP00000308541,9606.ENSP00000315130,9606.ENSP00000329374,9606.ENSP00000333203,9606.ENSP00000342850,9606.ENSP00000343445,9606.ENSP00000346839,9606.ENSP00000351190,9606.ENSP00000355627,9606.ENSP00000362924,9606.ENSP00000377783,9606.ENSP00000396688,9606.ENSP00000415769,9606.ENSP00000415941,9606.ENSP00000450540,9606.ENSP00000493985	CPB2,SERPIND1,C5,VTN,GPLD1,LTF,HRG,APOE,SERPINF1,LCN1,KLKB1,AMBP,ITIH4,ITIH1,AHSG,F2,CLU,SERPINA7,SERPINA5,SERPINA6,SERPINB4,FN1,ITIH2,AGT,GSN,PROS1,C4A,ITIH3,C4B,SERPINA3,KNG1
GO:0006958	Complement activation, classical pathway	14	40	1.9	4.68	1.66e-18	9606.ENSP00000223642,9606.ENSP00000263408,9606.ENSP00000299367,9606.ENSP00000315130,9606.ENSP00000322061,9606.ENSP00000354458,9606.ENSP00000356037,9606.ENSP00000360281,9606.ENSP00000363079,9606.ENSP00000363770,9606.ENSP00000378131,9606.ENSP00000385035,9606.ENSP00000396688,9606.ENSP00000415941	C5,C9,C2,CLU,C7,C8A,C4BPA,C8B,MBL2,C1QC,CFI,C1S,C4A,C4B
GO:0098542	Defense response to other organism	34	989	0.89	1.94	2.00e-18	9606.ENSP00000217407,9606.ENSP00000223642,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000253354,9606.ENSP00000255030,9606.ENSP00000255040,9606.ENSP00000261267,9606.ENSP00000263408,9606.ENSP00000265983,9606.ENSP00000291744,9606.ENSP00000292609,9606.ENSP00000296280,9606.ENSP00000299367,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000314299,9606.ENSP00000315130,9606.ENSP00000322061,9606.ENSP00000350425,9606.ENSP00000354458,9606.ENSP00000356037,9606.ENSP00000360281,9606.ENSP00000362924,9606.ENSP00000363079,9606.ENSP00000363770,9606.ENSP00000366109,9606.ENSP00000378131,9606.ENSP00000385035,9606.ENSP00000396688,9606.ENSP00000415941,9606.ENSP00000416561,9606.ENSP00000440066,9606.ENSP00000493985	LBP,C5,LTF,HRG,BPIFB1,CRP,APCS,LYZ,C9,HPX,FCN2,PGLYRP2,MASP1,C2,FGB,F2,CFHR1,CLU,C7,APOA4,C8A,C4BPA,C8B,GSN,MBL2,C1QC,ANXA1,CFI,C1S,C4A,C4B,CFB,JCHAIN,KNG1
GO:0052547	Regulation of peptidase activity	25	446	1.1	2.52	2.00e-17	9606.ENSP00000215727,9606.ENSP00000223642,9606.ENSP00000226218,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000254722,9606.ENSP00000263598,9606.ENSP00000265132,9606.ENSP00000266041,9606.ENSP00000273283,9606.ENSP00000273784,9606.ENSP00000329374,9606.ENSP00000333203,9606.ENSP00000342850,9606.ENSP00000343445,9606.ENSP00000346839,9606.ENSP00000351190,9606.ENSP00000355627,9606.ENSP00000362924,9606.ENSP00000377783,9606.ENSP00000396688,9606.ENSP00000415769,9606.ENSP00000415941,9606.ENSP00000450540,9606.ENSP00000493985	SERPIND1,C5,VTN,LTF,HRG,SERPINF1,LCN1,AMBP,ITIH4,ITIH1,AHSG,SERPINA7,SERPINA5,SERPINA6,SERPINB4,FN1,ITIH2,AGT,GSN,PROS1,C4A,ITIH3,C4B,SERPINA3,KNG1
GO:0052548	Regulation of endopeptidase activity	24	414	1.12	2.53	5.88e-17	9606.ENSP00000215727,9606.ENSP00000223642,9606.ENSP00000226218,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000254722,9606.ENSP00000263598,9606.ENSP00000265132,9606.ENSP00000266041,9606.ENSP00000273283,9606.ENSP00000273784,9606.ENSP00000329374,9606.ENSP00000333203,9606.ENSP00000342850,9606.ENSP00000343445,9606.ENSP00000351190,9606.ENSP00000355627,9606.ENSP00000362924,9606.ENSP00000377783,9606.ENSP00000396688,9606.ENSP00000415769,9606.ENSP00000415941,9606.ENSP00000450540,9606.ENSP00000493985	SERPIND1,C5,VTN,LTF,HRG,SERPINF1,LCN1,AMBP,ITIH4,ITIH1,AHSG,SERPINA7,SERPINA5,SERPINA6,SERPINB4,ITIH2,AGT,GSN,PROS1,C4A,ITIH3,C4B,SERPINA3,KNG1
GO:0044419	Biological process involved in interspecies interaction between organisms	38	1490	0.76	1.54	6.24e-17	9606.ENSP00000217407,9606.ENSP00000223642,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000252486,9606.ENSP00000253354,9606.ENSP00000255030,9606.ENSP00000255040,9606.ENSP00000261267,9606.ENSP00000263408,9606.ENSP00000265983,9606.ENSP00000291744,9606.ENSP00000292609,9606.ENSP00000296280,9606.ENSP00000299367,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000308938,9606.ENSP00000314299,9606.ENSP00000315130,9606.ENSP00000322061,9606.ENSP00000346839,9606.ENSP00000350425,9606.ENSP00000354458,9606.ENSP00000356037,9606.ENSP00000360281,9606.ENSP00000362924,9606.ENSP00000363079,9606.ENSP00000363770,9606.ENSP00000366109,9606.ENSP00000378131,9606.ENSP00000385035,9606.ENSP00000389814,9606.ENSP00000396688,9606.ENSP00000415941,9606.ENSP00000416561,9606.ENSP00000440066,9606.ENSP00000493985	LBP,C5,LTF,HRG,APOE,BPIFB1,CRP,APCS,LYZ,C9,HPX,FCN2,PGLYRP2,MASP1,C2,FGB,F2,PLG,CFHR1,CLU,C7,FN1,APOA4,C8A,C4BPA,C8B,GSN,MBL2,C1QC,ANXA1,CFI,C1S,ADIPOQ,C4A,C4B,CFB,JCHAIN,KNG1
GO:0006950	Response to stress	53	3358	0.55	1.08	8.60e-17	9606.ENSP00000181383,9606.ENSP00000215727,9606.ENSP00000217407,9606.ENSP00000223642,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000241052,9606.ENSP00000251595,9606.ENSP00000252486,9606.ENSP00000253354,9606.ENSP00000255030,9606.ENSP00000255040,9606.ENSP00000261267,9606.ENSP00000262919,9606.ENSP00000263408,9606.ENSP00000264690,9606.ENSP00000265132,9606.ENSP00000265983,9606.ENSP00000266041,9606.ENSP00000273784,9606.ENSP00000278222,9606.ENSP00000291744,9606.ENSP00000292609,9606.ENSP00000296280,9606.ENSP00000299367,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000308938,9606.ENSP00000314299,9606.ENSP00000315130,9606.ENSP00000322061,9606.ENSP00000345179,9606.ENSP00000346839,9606.ENSP00000350425,9606.ENSP00000354458,9606.ENSP00000355627,9606.ENSP00000356037,9606.ENSP00000357156,9606.ENSP00000360281,9606.ENSP00000362924,9606.ENSP00000363079,9606.ENSP00000363770,9606.ENSP00000366109,9606.ENSP00000377783,9606.ENSP00000378131,9606.ENSP00000385035,9606.ENSP00000389814,9606.ENSP00000396688,9606.ENSP00000415941,9606.ENSP00000416561,9606.ENSP00000440066,9606.ENSP00000450540,9606.ENSP00000493985	CPB2,SERPIND1,LBP,C5,LTF,HRG,CAT,HBA2,APOE,BPIFB1,CRP,APCS,LYZ,ATRN,C9,KLKB1,AMBP,HPX,ITIH4,AHSG,SAA4,FCN2,PGLYRP2,MASP1,C2,FGB,F2,PLG,CFHR1,CLU,C7,APOD,FN1,APOA4,C8A,AGT,C4BPA,CD5L,C8B,GSN,MBL2,C1QC,ANXA1,PROS1,CFI,C1S,ADIPOQ,C4A,C4B,CFB,JCHAIN,SERPINA3,KNG1
GO:0006955	Immune response	36	1321	0.79	1.61	9.51e-17	9606.ENSP00000217407,9606.ENSP00000223642,9606.ENSP00000226218,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000253354,9606.ENSP00000255030,9606.ENSP00000255040,9606.ENSP00000261267,9606.ENSP00000263408,9606.ENSP00000265983,9606.ENSP00000291744,9606.ENSP00000292609,9606.ENSP00000296280,9606.ENSP00000299367,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000314299,9606.ENSP00000315130,9606.ENSP00000322061,9606.ENSP00000350425,9606.ENSP00000354458,9606.ENSP00000356037,9606.ENSP00000360281,9606.ENSP00000360687,9606.ENSP00000362924,9606.ENSP00000363079,9606.ENSP00000363770,9606.ENSP00000366109,9606.ENSP00000378131,9606.ENSP00000385035,9606.ENSP00000396688,9606.ENSP00000415941,9606.ENSP00000416561,9606.ENSP00000440066,9606.ENSP00000493985	LBP,C5,VTN,LTF,HRG,BPIFB1,CRP,APCS,LYZ,C9,HPX,FCN2,PGLYRP2,MASP1,C2,FGB,F2,CFHR1,CLU,C7,APOA4,C8A,C4BPA,C8B,PTGDS,GSN,MBL2,C1QC,ANXA1,CFI,C1S,C4A,C4B,CFB,JCHAIN,KNG1
GO:0045087	Innate immune response	29	754	0.94	2.0	1.35e-16	9606.ENSP00000217407,9606.ENSP00000223642,9606.ENSP00000231751,9606.ENSP00000253354,9606.ENSP00000255030,9606.ENSP00000255040,9606.ENSP00000263408,9606.ENSP00000265983,9606.ENSP00000291744,9606.ENSP00000292609,9606.ENSP00000296280,9606.ENSP00000299367,9606.ENSP00000306099,9606.ENSP00000315130,9606.ENSP00000322061,9606.ENSP00000350425,9606.ENSP00000354458,9606.ENSP00000356037,9606.ENSP00000360281,9606.ENSP00000362924,9606.ENSP00000363079,9606.ENSP00000363770,9606.ENSP00000366109,9606.ENSP00000378131,9606.ENSP00000385035,9606.ENSP00000396688,9606.ENSP00000415941,9606.ENSP00000416561,9606.ENSP00000440066	LBP,C5,LTF,BPIFB1,CRP,APCS,C9,HPX,FCN2,PGLYRP2,MASP1,C2,FGB,CLU,C7,APOA4,C8A,C4BPA,C8B,GSN,MBL2,C1QC,ANXA1,CFI,C1S,C4A,C4B,CFB,JCHAIN
GO:0050776	Regulation of immune response	30	844	0.91	1.89	2.15e-16	9606.ENSP00000217407,9606.ENSP00000223642,9606.ENSP00000230036,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000252486,9606.ENSP00000253354,9606.ENSP00000263408,9606.ENSP00000265132,9606.ENSP00000265983,9606.ENSP00000291744,9606.ENSP00000292609,9606.ENSP00000296280,9606.ENSP00000299367,9606.ENSP00000314299,9606.ENSP00000315130,9606.ENSP00000322061,9606.ENSP00000343445,9606.ENSP00000354458,9606.ENSP00000356037,9606.ENSP00000357156,9606.ENSP00000360281,9606.ENSP00000363079,9606.ENSP00000363770,9606.ENSP00000366109,9606.ENSP00000378131,9606.ENSP00000385035,9606.ENSP00000396688,9606.ENSP00000415941,9606.ENSP00000416561	LBP,C5,GPLD1,LTF,HRG,APOE,BPIFB1,C9,AMBP,HPX,FCN2,PGLYRP2,MASP1,C2,CFHR1,CLU,C7,SERPINB4,C8A,C4BPA,CD5L,C8B,MBL2,C1QC,ANXA1,CFI,C1S,C4A,C4B,CFB
GO:0051707	Response to other organism	35	1328	0.78	1.54	8.91e-16	9606.ENSP00000217407,9606.ENSP00000223642,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000253354,9606.ENSP00000255030,9606.ENSP00000255040,9606.ENSP00000261267,9606.ENSP00000263408,9606.ENSP00000265983,9606.ENSP00000291744,9606.ENSP00000292609,9606.ENSP00000296280,9606.ENSP00000299367,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000314299,9606.ENSP00000315130,9606.ENSP00000322061,9606.ENSP00000350425,9606.ENSP00000354458,9606.ENSP00000356037,9606.ENSP00000360281,9606.ENSP00000362924,9606.ENSP00000363079,9606.ENSP00000363770,9606.ENSP00000366109,9606.ENSP00000378131,9606.ENSP00000385035,9606.ENSP00000389814,9606.ENSP00000396688,9606.ENSP00000415941,9606.ENSP00000416561,9606.ENSP00000440066,9606.ENSP00000493985	LBP,C5,LTF,HRG,BPIFB1,CRP,APCS,LYZ,C9,HPX,FCN2,PGLYRP2,MASP1,C2,FGB,F2,CFHR1,CLU,C7,APOA4,C8A,C4BPA,C8B,GSN,MBL2,C1QC,ANXA1,CFI,C1S,ADIPOQ,C4A,C4B,CFB,JCHAIN,KNG1
GO:0002682	Regulation of immune system process	36	1438	0.75	1.49	1.08e-15	9606.ENSP00000217407,9606.ENSP00000223642,9606.ENSP00000230036,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000252486,9606.ENSP00000253354,9606.ENSP00000255040,9606.ENSP00000263408,9606.ENSP00000265132,9606.ENSP00000265983,9606.ENSP00000291009,9606.ENSP00000291744,9606.ENSP00000292609,9606.ENSP00000296280,9606.ENSP00000299367,9606.ENSP00000314299,9606.ENSP00000315130,9606.ENSP00000322061,9606.ENSP00000343445,9606.ENSP00000345179,9606.ENSP00000346839,9606.ENSP00000354458,9606.ENSP00000356037,9606.ENSP00000357156,9606.ENSP00000360281,9606.ENSP00000360522,9606.ENSP00000363079,9606.ENSP00000363770,9606.ENSP00000366109,9606.ENSP00000378131,9606.ENSP00000385035,9606.ENSP00000389814,9606.ENSP00000396688,9606.ENSP00000415941,9606.ENSP00000416561	LBP,C5,GPLD1,LTF,HRG,APOE,BPIFB1,APCS,C9,AMBP,HPX,PIP,FCN2,PGLYRP2,MASP1,C2,CFHR1,CLU,C7,SERPINB4,APOD,FN1,C8A,C4BPA,CD5L,C8B,RBP4,MBL2,C1QC,ANXA1,CFI,C1S,ADIPOQ,C4A,C4B,CFB
GO:0002252	Immune effector process	22	375	1.12	2.43	1.24e-15	9606.ENSP00000217407,9606.ENSP00000223642,9606.ENSP00000255030,9606.ENSP00000263408,9606.ENSP00000291744,9606.ENSP00000296280,9606.ENSP00000299367,9606.ENSP00000308541,9606.ENSP00000314299,9606.ENSP00000315130,9606.ENSP00000322061,9606.ENSP00000354458,9606.ENSP00000356037,9606.ENSP00000360281,9606.ENSP00000360687,9606.ENSP00000363079,9606.ENSP00000363770,9606.ENSP00000378131,9606.ENSP00000385035,9606.ENSP00000396688,9606.ENSP00000415941,9606.ENSP00000416561	LBP,C5,CRP,C9,FCN2,MASP1,C2,F2,CFHR1,CLU,C7,C8A,C4BPA,C8B,PTGDS,MBL2,C1QC,CFI,C1S,C4A,C4B,CFB
GO:0043086	Negative regulation of catalytic activity	28	771	0.92	1.87	2.09e-15	9606.ENSP00000215727,9606.ENSP00000223642,9606.ENSP00000226218,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000252486,9606.ENSP00000254722,9606.ENSP00000255040,9606.ENSP00000263598,9606.ENSP00000265132,9606.ENSP00000266041,9606.ENSP00000273283,9606.ENSP00000273784,9606.ENSP00000329374,9606.ENSP00000333203,9606.ENSP00000342850,9606.ENSP00000343445,9606.ENSP00000351190,9606.ENSP00000355627,9606.ENSP00000366109,9606.ENSP00000377783,9606.ENSP00000389814,9606.ENSP00000396688,9606.ENSP00000415769,9606.ENSP00000415941,9606.ENSP00000450540,9606.ENSP00000465356,9606.ENSP00000493985	SERPIND1,C5,VTN,LTF,HRG,APOE,SERPINF1,APCS,LCN1,AMBP,ITIH4,ITIH1,AHSG,SERPINA7,SERPINA5,SERPINA6,SERPINB4,ITIH2,AGT,ANXA1,PROS1,ADIPOQ,C4A,ITIH3,C4B,SERPINA3,APOC1,KNG1
GO:0051336	Regulation of hydrolase activity	31	1011	0.84	1.69	2.09e-15	9606.ENSP00000215727,9606.ENSP00000223642,9606.ENSP00000226218,9606.ENSP00000230036,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000254722,9606.ENSP00000255040,9606.ENSP00000263598,9606.ENSP00000265132,9606.ENSP00000266041,9606.ENSP00000273283,9606.ENSP00000273784,9606.ENSP00000281419,9606.ENSP00000329374,9606.ENSP00000333203,9606.ENSP00000342850,9606.ENSP00000343445,9606.ENSP00000346839,9606.ENSP00000350425,9606.ENSP00000351190,9606.ENSP00000355627,9606.ENSP00000362924,9606.ENSP00000366109,9606.ENSP00000377783,9606.ENSP00000396688,9606.ENSP00000415769,9606.ENSP00000415941,9606.ENSP00000450540,9606.ENSP00000465356,9606.ENSP00000493985	SERPIND1,C5,VTN,GPLD1,LTF,HRG,SERPINF1,APCS,LCN1,AMBP,ITIH4,ITIH1,AHSG,ASAP2,SERPINA7,SERPINA5,SERPINA6,SERPINB4,FN1,APOA4,ITIH2,AGT,GSN,ANXA1,PROS1,C4A,ITIH3,C4B,SERPINA3,APOC1,KNG1
GO:0051248	Negative regulation of protein metabolic process	31	1038	0.83	1.65	3.96e-15	9606.ENSP00000181383,9606.ENSP00000215727,9606.ENSP00000223642,9606.ENSP00000226218,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000252486,9606.ENSP00000254722,9606.ENSP00000255040,9606.ENSP00000263598,9606.ENSP00000265132,9606.ENSP00000266041,9606.ENSP00000273283,9606.ENSP00000273784,9606.ENSP00000308541,9606.ENSP00000315130,9606.ENSP00000329374,9606.ENSP00000333203,9606.ENSP00000342850,9606.ENSP00000343445,9606.ENSP00000345179,9606.ENSP00000351190,9606.ENSP00000355627,9606.ENSP00000370473,9606.ENSP00000377783,9606.ENSP00000389814,9606.ENSP00000396688,9606.ENSP00000415769,9606.ENSP00000415941,9606.ENSP00000450540,9606.ENSP00000493985	CPB2,SERPIND1,C5,VTN,LTF,HRG,APOE,SERPINF1,APCS,LCN1,AMBP,ITIH4,ITIH1,AHSG,F2,CLU,SERPINA7,SERPINA5,SERPINA6,SERPINB4,APOD,ITIH2,AGT,IGFBP3,PROS1,ADIPOQ,C4A,ITIH3,C4B,SERPINA3,KNG1
GO:0002253	Activation of immune response	19	271	1.2	2.53	1.31e-14	9606.ENSP00000223642,9606.ENSP00000230036,9606.ENSP00000263408,9606.ENSP00000291744,9606.ENSP00000296280,9606.ENSP00000299367,9606.ENSP00000314299,9606.ENSP00000315130,9606.ENSP00000322061,9606.ENSP00000354458,9606.ENSP00000356037,9606.ENSP00000360281,9606.ENSP00000363079,9606.ENSP00000363770,9606.ENSP00000378131,9606.ENSP00000385035,9606.ENSP00000396688,9606.ENSP00000415941,9606.ENSP00000416561	C5,GPLD1,C9,FCN2,MASP1,C2,CFHR1,CLU,C7,C8A,C4BPA,C8B,MBL2,C1QC,CFI,C1S,C4A,C4B,CFB
GO:0050778	Positive regulation of immune response	23	502	1.02	2.05	2.49e-14	9606.ENSP00000217407,9606.ENSP00000223642,9606.ENSP00000230036,9606.ENSP00000232003,9606.ENSP00000263408,9606.ENSP00000265983,9606.ENSP00000291744,9606.ENSP00000296280,9606.ENSP00000299367,9606.ENSP00000314299,9606.ENSP00000315130,9606.ENSP00000322061,9606.ENSP00000354458,9606.ENSP00000356037,9606.ENSP00000360281,9606.ENSP00000363079,9606.ENSP00000363770,9606.ENSP00000366109,9606.ENSP00000378131,9606.ENSP00000385035,9606.ENSP00000396688,9606.ENSP00000415941,9606.ENSP00000416561	LBP,C5,GPLD1,HRG,C9,HPX,FCN2,MASP1,C2,CFHR1,CLU,C7,C8A,C4BPA,C8B,MBL2,C1QC,ANXA1,CFI,C1S,C4A,C4B,CFB
GO:0009605	Response to external stimulus	41	2355	0.6	1.09	3.70e-13	9606.ENSP00000215727,9606.ENSP00000217407,9606.ENSP00000222381,9606.ENSP00000223642,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000241052,9606.ENSP00000252486,9606.ENSP00000253354,9606.ENSP00000255030,9606.ENSP00000255040,9606.ENSP00000261267,9606.ENSP00000263408,9606.ENSP00000264381,9606.ENSP00000265983,9606.ENSP00000291744,9606.ENSP00000292609,9606.ENSP00000296280,9606.ENSP00000299367,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000314299,9606.ENSP00000315130,9606.ENSP00000322061,9606.ENSP00000350425,9606.ENSP00000354458,9606.ENSP00000355627,9606.ENSP00000356037,9606.ENSP00000360281,9606.ENSP00000362924,9606.ENSP00000363079,9606.ENSP00000363770,9606.ENSP00000366109,9606.ENSP00000378131,9606.ENSP00000385035,9606.ENSP00000389814,9606.ENSP00000396688,9606.ENSP00000415941,9606.ENSP00000416561,9606.ENSP00000440066,9606.ENSP00000493985	SERPIND1,LBP,PON1,C5,LTF,HRG,CAT,APOE,BPIFB1,CRP,APCS,LYZ,C9,BCHE,HPX,FCN2,PGLYRP2,MASP1,C2,FGB,F2,CFHR1,CLU,C7,APOA4,C8A,AGT,C4BPA,C8B,GSN,MBL2,C1QC,ANXA1,CFI,C1S,ADIPOQ,C4A,C4B,CFB,JCHAIN,KNG1
GO:0044092	Negative regulation of molecular function	30	1143	0.77	1.44	3.91e-13	9606.ENSP00000215727,9606.ENSP00000223642,9606.ENSP00000226218,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000241052,9606.ENSP00000252486,9606.ENSP00000254722,9606.ENSP00000255040,9606.ENSP00000263598,9606.ENSP00000265132,9606.ENSP00000266041,9606.ENSP00000273283,9606.ENSP00000273784,9606.ENSP00000314299,9606.ENSP00000329374,9606.ENSP00000333203,9606.ENSP00000342850,9606.ENSP00000343445,9606.ENSP00000351190,9606.ENSP00000355627,9606.ENSP00000366109,9606.ENSP00000377783,9606.ENSP00000389814,9606.ENSP00000396688,9606.ENSP00000415769,9606.ENSP00000415941,9606.ENSP00000450540,9606.ENSP00000465356,9606.ENSP00000493985	SERPIND1,C5,VTN,LTF,HRG,CAT,APOE,SERPINF1,APCS,LCN1,AMBP,ITIH4,ITIH1,AHSG,CFHR1,SERPINA7,SERPINA5,SERPINA6,SERPINB4,ITIH2,AGT,ANXA1,PROS1,ADIPOQ,C4A,ITIH3,C4B,SERPINA3,APOC1,KNG1
GO:0002376	Immune system process	39	2121	0.62	1.13	4.42e-13	9606.ENSP00000217407,9606.ENSP00000223642,9606.ENSP00000226218,9606.ENSP00000230036,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000253354,9606.ENSP00000255030,9606.ENSP00000255040,9606.ENSP00000261267,9606.ENSP00000263408,9606.ENSP00000265983,9606.ENSP00000291744,9606.ENSP00000292609,9606.ENSP00000296280,9606.ENSP00000299367,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000308938,9606.ENSP00000314299,9606.ENSP00000315130,9606.ENSP00000322061,9606.ENSP00000350425,9606.ENSP00000354458,9606.ENSP00000356037,9606.ENSP00000357156,9606.ENSP00000360281,9606.ENSP00000360687,9606.ENSP00000362924,9606.ENSP00000363079,9606.ENSP00000363770,9606.ENSP00000366109,9606.ENSP00000378131,9606.ENSP00000385035,9606.ENSP00000396688,9606.ENSP00000415941,9606.ENSP00000416561,9606.ENSP00000440066,9606.ENSP00000493985	LBP,C5,VTN,GPLD1,LTF,HRG,BPIFB1,CRP,APCS,LYZ,C9,HPX,FCN2,PGLYRP2,MASP1,C2,FGB,F2,PLG,CFHR1,CLU,C7,APOA4,C8A,C4BPA,CD5L,C8B,PTGDS,GSN,MBL2,C1QC,ANXA1,CFI,C1S,C4A,C4B,CFB,JCHAIN,KNG1
GO:0002443	Leukocyte mediated immunity	16	211	1.23	2.37	1.41e-12	9606.ENSP00000223642,9606.ENSP00000263408,9606.ENSP00000299367,9606.ENSP00000308541,9606.ENSP00000315130,9606.ENSP00000322061,9606.ENSP00000354458,9606.ENSP00000356037,9606.ENSP00000360281,9606.ENSP00000360687,9606.ENSP00000363079,9606.ENSP00000363770,9606.ENSP00000378131,9606.ENSP00000385035,9606.ENSP00000396688,9606.ENSP00000415941	C5,C9,C2,F2,CLU,C7,C8A,C4BPA,C8B,PTGDS,MBL2,C1QC,CFI,C1S,C4A,C4B
GO:0050896	Response to stimulus	70	7835	0.31	0.64	5.08e-12	9606.ENSP00000181383,9606.ENSP00000215727,9606.ENSP00000217407,9606.ENSP00000222381,9606.ENSP00000223642,9606.ENSP00000226218,9606.ENSP00000230036,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000241052,9606.ENSP00000251595,9606.ENSP00000252486,9606.ENSP00000253354,9606.ENSP00000254722,9606.ENSP00000255030,9606.ENSP00000255040,9606.ENSP00000261267,9606.ENSP00000261714,9606.ENSP00000262919,9606.ENSP00000263408,9606.ENSP00000263598,9606.ENSP00000263946,9606.ENSP00000264381,9606.ENSP00000264690,9606.ENSP00000265132,9606.ENSP00000265627,9606.ENSP00000265983,9606.ENSP00000266041,9606.ENSP00000273784,9606.ENSP00000275428,9606.ENSP00000278222,9606.ENSP00000291009,9606.ENSP00000291744,9606.ENSP00000292609,9606.ENSP00000296280,9606.ENSP00000299367,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000308938,9606.ENSP00000314299,9606.ENSP00000315130,9606.ENSP00000322061,9606.ENSP00000345179,9606.ENSP00000346839,9606.ENSP00000350425,9606.ENSP00000354458,9606.ENSP00000355627,9606.ENSP00000356037,9606.ENSP00000357156,9606.ENSP00000357695,9606.ENSP00000360281,9606.ENSP00000360522,9606.ENSP00000360687,9606.ENSP00000362924,9606.ENSP00000363079,9606.ENSP00000363770,9606.ENSP00000365081,9606.ENSP00000366109,9606.ENSP00000370473,9606.ENSP00000377783,9606.ENSP00000378131,9606.ENSP00000385035,9606.ENSP00000389814,9606.ENSP00000396688,9606.ENSP00000415941,9606.ENSP00000416561,9606.ENSP00000416683,9606.ENSP00000440066,9606.ENSP00000450540,9606.ENSP00000493985	CPB2,SERPIND1,LBP,PON1,C5,VTN,GPLD1,LTF,HRG,CAT,HBA2,APOE,BPIFB1,SERPINF1,CRP,APCS,LYZ,BLMH,ATRN,C9,LCN1,PKP1,BCHE,KLKB1,AMBP,PON3,HPX,ITIH4,AHSG,GGCT,SAA4,PIP,FCN2,PGLYRP2,MASP1,C2,FGB,F2,PLG,CFHR1,CLU,C7,APOD,FN1,APOA4,C8A,AGT,C4BPA,CD5L,S100A16,C8B,RBP4,PTGDS,GSN,MBL2,C1QC,APOM,ANXA1,IGFBP3,PROS1,CFI,C1S,ADIPOQ,C4A,C4B,CFB,IGFALS,JCHAIN,SERPINA3,KNG1
GO:0006953	Acute-phase response	10	42	1.73	2.94	9.40e-12	9606.ENSP00000217407,9606.ENSP00000255030,9606.ENSP00000255040,9606.ENSP00000266041,9606.ENSP00000273784,9606.ENSP00000278222,9606.ENSP00000308541,9606.ENSP00000346839,9606.ENSP00000363079,9606.ENSP00000450540	LBP,CRP,APCS,ITIH4,AHSG,SAA4,F2,FN1,MBL2,SERPINA3
GO:0051241	Negative regulation of multicellular organismal process	27	1035	0.77	1.36	1.58e-11	9606.ENSP00000181383,9606.ENSP00000217407,9606.ENSP00000226218,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000252486,9606.ENSP00000254722,9606.ENSP00000255040,9606.ENSP00000264690,9606.ENSP00000273784,9606.ENSP00000292609,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000308938,9606.ENSP00000345179,9606.ENSP00000346839,9606.ENSP00000350425,9606.ENSP00000355627,9606.ENSP00000360522,9606.ENSP00000360687,9606.ENSP00000363770,9606.ENSP00000365081,9606.ENSP00000366109,9606.ENSP00000377783,9606.ENSP00000389814,9606.ENSP00000465356,9606.ENSP00000493985	CPB2,LBP,VTN,LTF,HRG,APOE,SERPINF1,APCS,KLKB1,AHSG,PGLYRP2,FGB,F2,PLG,APOD,FN1,APOA4,AGT,RBP4,PTGDS,C1QC,APOM,ANXA1,PROS1,ADIPOQ,APOC1,KNG1
GO:0030195	Negative regulation of blood coagulation	10	46	1.69	2.83	1.92e-11	9606.ENSP00000181383,9606.ENSP00000226218,9606.ENSP00000232003,9606.ENSP00000252486,9606.ENSP00000264690,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000308938,9606.ENSP00000377783,9606.ENSP00000493985	CPB2,VTN,HRG,APOE,KLKB1,FGB,F2,PLG,PROS1,KNG1
GO:0061045	Negative regulation of wound healing	11	69	1.56	2.69	1.98e-11	9606.ENSP00000181383,9606.ENSP00000226218,9606.ENSP00000232003,9606.ENSP00000252486,9606.ENSP00000255040,9606.ENSP00000264690,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000308938,9606.ENSP00000377783,9606.ENSP00000493985	CPB2,VTN,HRG,APOE,APCS,KLKB1,FGB,F2,PLG,PROS1,KNG1
GO:0032101	Regulation of response to external stimulus	26	964	0.79	1.37	2.27e-11	9606.ENSP00000181383,9606.ENSP00000217407,9606.ENSP00000223642,9606.ENSP00000226218,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000252486,9606.ENSP00000254722,9606.ENSP00000255040,9606.ENSP00000264690,9606.ENSP00000265983,9606.ENSP00000273784,9606.ENSP00000291744,9606.ENSP00000292609,9606.ENSP00000296280,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000308938,9606.ENSP00000343445,9606.ENSP00000355627,9606.ENSP00000363079,9606.ENSP00000366109,9606.ENSP00000377783,9606.ENSP00000378131,9606.ENSP00000389814,9606.ENSP00000493985	CPB2,LBP,C5,VTN,LTF,HRG,APOE,SERPINF1,APCS,KLKB1,HPX,AHSG,FCN2,PGLYRP2,MASP1,FGB,F2,PLG,SERPINB4,AGT,MBL2,ANXA1,PROS1,CFI,ADIPOQ,KNG1
GO:1903027	Regulation of opsonization	8	18	2.0	2.96	5.13e-11	9606.ENSP00000291744,9606.ENSP00000296280,9606.ENSP00000299367,9606.ENSP00000356037,9606.ENSP00000363079,9606.ENSP00000396688,9606.ENSP00000415941,9606.ENSP00000416561	FCN2,MASP1,C2,C4BPA,MBL2,C4A,C4B,CFB
GO:0002526	Acute inflammatory response	11	80	1.49	2.49	7.49e-11	9606.ENSP00000217407,9606.ENSP00000255030,9606.ENSP00000255040,9606.ENSP00000264690,9606.ENSP00000266041,9606.ENSP00000273784,9606.ENSP00000278222,9606.ENSP00000308541,9606.ENSP00000346839,9606.ENSP00000363079,9606.ENSP00000450540	LBP,CRP,APCS,KLKB1,ITIH4,AHSG,SAA4,F2,FN1,MBL2,SERPINA3
GO:0006954	Inflammatory response	20	538	0.93	1.59	9.89e-11	9606.ENSP00000217407,9606.ENSP00000223642,9606.ENSP00000255030,9606.ENSP00000255040,9606.ENSP00000261267,9606.ENSP00000262919,9606.ENSP00000264690,9606.ENSP00000266041,9606.ENSP00000273784,9606.ENSP00000278222,9606.ENSP00000308541,9606.ENSP00000315130,9606.ENSP00000346839,9606.ENSP00000357156,9606.ENSP00000363079,9606.ENSP00000366109,9606.ENSP00000396688,9606.ENSP00000415941,9606.ENSP00000450540,9606.ENSP00000493985	LBP,C5,CRP,APCS,LYZ,ATRN,KLKB1,ITIH4,AHSG,SAA4,F2,CLU,FN1,CD5L,MBL2,ANXA1,C4A,C4B,SERPINA3,KNG1
GO:0048519	Negative regulation of biological process	56	5313	0.38	0.71	1.31e-10	9606.ENSP00000181383,9606.ENSP00000215727,9606.ENSP00000217407,9606.ENSP00000223642,9606.ENSP00000226218,9606.ENSP00000230036,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000241052,9606.ENSP00000252486,9606.ENSP00000253354,9606.ENSP00000254722,9606.ENSP00000255030,9606.ENSP00000255040,9606.ENSP00000263598,9606.ENSP00000263946,9606.ENSP00000264381,9606.ENSP00000264690,9606.ENSP00000265132,9606.ENSP00000265627,9606.ENSP00000266041,9606.ENSP00000273283,9606.ENSP00000273784,9606.ENSP00000291009,9606.ENSP00000292609,9606.ENSP00000296280,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000308938,9606.ENSP00000315130,9606.ENSP00000329374,9606.ENSP00000333203,9606.ENSP00000342850,9606.ENSP00000343445,9606.ENSP00000345179,9606.ENSP00000346839,9606.ENSP00000350425,9606.ENSP00000351190,9606.ENSP00000355627,9606.ENSP00000356037,9606.ENSP00000360522,9606.ENSP00000360687,9606.ENSP00000362924,9606.ENSP00000363079,9606.ENSP00000363770,9606.ENSP00000365081,9606.ENSP00000366109,9606.ENSP00000370473,9606.ENSP00000377783,9606.ENSP00000389814,9606.ENSP00000396688,9606.ENSP00000415769,9606.ENSP00000415941,9606.ENSP00000450540,9606.ENSP00000465356,9606.ENSP00000493985	CPB2,SERPIND1,LBP,C5,VTN,GPLD1,LTF,HRG,CAT,APOE,BPIFB1,SERPINF1,CRP,APCS,LCN1,PKP1,BCHE,KLKB1,AMBP,PON3,ITIH4,ITIH1,AHSG,PIP,PGLYRP2,MASP1,FGB,F2,PLG,CLU,SERPINA7,SERPINA5,SERPINA6,SERPINB4,APOD,FN1,APOA4,ITIH2,AGT,C4BPA,RBP4,PTGDS,GSN,MBL2,C1QC,APOM,ANXA1,IGFBP3,PROS1,ADIPOQ,C4A,ITIH3,C4B,SERPINA3,APOC1,KNG1
GO:0002684	Positive regulation of immune system process	24	874	0.79	1.34	1.52e-10	9606.ENSP00000217407,9606.ENSP00000223642,9606.ENSP00000230036,9606.ENSP00000232003,9606.ENSP00000263408,9606.ENSP00000265983,9606.ENSP00000291744,9606.ENSP00000296280,9606.ENSP00000299367,9606.ENSP00000314299,9606.ENSP00000315130,9606.ENSP00000322061,9606.ENSP00000354458,9606.ENSP00000356037,9606.ENSP00000360281,9606.ENSP00000360522,9606.ENSP00000363079,9606.ENSP00000363770,9606.ENSP00000366109,9606.ENSP00000378131,9606.ENSP00000385035,9606.ENSP00000396688,9606.ENSP00000415941,9606.ENSP00000416561	LBP,C5,GPLD1,HRG,C9,HPX,FCN2,MASP1,C2,CFHR1,CLU,C7,C8A,C4BPA,C8B,RBP4,MBL2,C1QC,ANXA1,CFI,C1S,C4A,C4B,CFB
GO:0002250	Adaptive immune response	17	359	1.03	1.75	1.74e-10	9606.ENSP00000223642,9606.ENSP00000263408,9606.ENSP00000299367,9606.ENSP00000306099,9606.ENSP00000315130,9606.ENSP00000322061,9606.ENSP00000354458,9606.ENSP00000356037,9606.ENSP00000360281,9606.ENSP00000363079,9606.ENSP00000363770,9606.ENSP00000366109,9606.ENSP00000378131,9606.ENSP00000385035,9606.ENSP00000396688,9606.ENSP00000415941,9606.ENSP00000440066	C5,C9,C2,FGB,CLU,C7,C8A,C4BPA,C8B,MBL2,C1QC,ANXA1,CFI,C1S,C4A,C4B,JCHAIN
GO:0050790	Regulation of catalytic activity	37	2370	0.55	0.93	3.39e-10	9606.ENSP00000215727,9606.ENSP00000223642,9606.ENSP00000226218,9606.ENSP00000230036,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000252486,9606.ENSP00000254722,9606.ENSP00000255040,9606.ENSP00000263598,9606.ENSP00000265132,9606.ENSP00000266041,9606.ENSP00000273283,9606.ENSP00000273784,9606.ENSP00000281419,9606.ENSP00000308541,9606.ENSP00000315130,9606.ENSP00000319464,9606.ENSP00000329374,9606.ENSP00000333203,9606.ENSP00000342850,9606.ENSP00000343445,9606.ENSP00000346839,9606.ENSP00000350425,9606.ENSP00000351190,9606.ENSP00000355627,9606.ENSP00000362924,9606.ENSP00000366109,9606.ENSP00000370473,9606.ENSP00000377783,9606.ENSP00000389814,9606.ENSP00000396688,9606.ENSP00000415769,9606.ENSP00000415941,9606.ENSP00000450540,9606.ENSP00000465356,9606.ENSP00000493985	SERPIND1,C5,VTN,GPLD1,LTF,HRG,APOE,SERPINF1,APCS,LCN1,AMBP,ITIH4,ITIH1,AHSG,ASAP2,F2,CLU,CPN2,SERPINA7,SERPINA5,SERPINA6,SERPINB4,FN1,APOA4,ITIH2,AGT,GSN,ANXA1,IGFBP3,PROS1,ADIPOQ,C4A,ITIH3,C4B,SERPINA3,APOC1,KNG1
GO:0061041	Regulation of wound healing	12	130	1.32	2.15	3.86e-10	9606.ENSP00000181383,9606.ENSP00000226218,9606.ENSP00000232003,9606.ENSP00000252486,9606.ENSP00000255040,9606.ENSP00000264690,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000308938,9606.ENSP00000366109,9606.ENSP00000377783,9606.ENSP00000493985	CPB2,VTN,HRG,APOE,APCS,KLKB1,FGB,F2,PLG,ANXA1,PROS1,KNG1
GO:0048584	Positive regulation of response to stimulus	35	2131	0.57	0.96	4.32e-10	9606.ENSP00000181383,9606.ENSP00000217407,9606.ENSP00000223642,9606.ENSP00000226218,9606.ENSP00000230036,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000241052,9606.ENSP00000252486,9606.ENSP00000263408,9606.ENSP00000265983,9606.ENSP00000291744,9606.ENSP00000296280,9606.ENSP00000299367,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000308938,9606.ENSP00000314299,9606.ENSP00000315130,9606.ENSP00000322061,9606.ENSP00000346839,9606.ENSP00000354458,9606.ENSP00000355627,9606.ENSP00000356037,9606.ENSP00000360281,9606.ENSP00000363079,9606.ENSP00000363770,9606.ENSP00000366109,9606.ENSP00000370473,9606.ENSP00000378131,9606.ENSP00000385035,9606.ENSP00000389814,9606.ENSP00000396688,9606.ENSP00000415941,9606.ENSP00000416561	CPB2,LBP,C5,VTN,GPLD1,LTF,HRG,CAT,APOE,C9,HPX,FCN2,MASP1,C2,FGB,F2,PLG,CFHR1,CLU,C7,FN1,C8A,AGT,C4BPA,C8B,MBL2,C1QC,ANXA1,IGFBP3,CFI,C1S,ADIPOQ,C4A,C4B,CFB
GO:0048583	Regulation of response to stimulus	47	3931	0.43	0.76	7.00e-10	9606.ENSP00000181383,9606.ENSP00000217407,9606.ENSP00000223642,9606.ENSP00000226218,9606.ENSP00000230036,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000241052,9606.ENSP00000252486,9606.ENSP00000253354,9606.ENSP00000254722,9606.ENSP00000255040,9606.ENSP00000263408,9606.ENSP00000264690,9606.ENSP00000265132,9606.ENSP00000265983,9606.ENSP00000273784,9606.ENSP00000291744,9606.ENSP00000292609,9606.ENSP00000296280,9606.ENSP00000299367,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000308938,9606.ENSP00000314299,9606.ENSP00000315130,9606.ENSP00000322061,9606.ENSP00000343445,9606.ENSP00000345179,9606.ENSP00000346839,9606.ENSP00000354458,9606.ENSP00000355627,9606.ENSP00000356037,9606.ENSP00000357156,9606.ENSP00000360281,9606.ENSP00000363079,9606.ENSP00000363770,9606.ENSP00000366109,9606.ENSP00000370473,9606.ENSP00000377783,9606.ENSP00000378131,9606.ENSP00000385035,9606.ENSP00000389814,9606.ENSP00000396688,9606.ENSP00000415941,9606.ENSP00000416561,9606.ENSP00000493985	CPB2,LBP,C5,VTN,GPLD1,LTF,HRG,CAT,APOE,BPIFB1,SERPINF1,APCS,C9,KLKB1,AMBP,HPX,AHSG,FCN2,PGLYRP2,MASP1,C2,FGB,F2,PLG,CFHR1,CLU,C7,SERPINB4,APOD,FN1,C8A,AGT,C4BPA,CD5L,C8B,MBL2,C1QC,ANXA1,IGFBP3,PROS1,CFI,C1S,ADIPOQ,C4A,C4B,CFB,KNG1
GO:1903028	Positive regulation of opsonization	7	16	2.0	2.56	1.53e-09	9606.ENSP00000291744,9606.ENSP00000296280,9606.ENSP00000299367,9606.ENSP00000363079,9606.ENSP00000396688,9606.ENSP00000415941,9606.ENSP00000416561	FCN2,MASP1,C2,MBL2,C4A,C4B,CFB
GO:0042730	Fibrinolysis	7	19	1.92	2.42	3.93e-09	9606.ENSP00000181383,9606.ENSP00000232003,9606.ENSP00000264690,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000308938,9606.ENSP00000377783	CPB2,HRG,KLKB1,FGB,F2,PLG,PROS1
GO:0002697	Regulation of immune effector process	16	383	0.98	1.52	4.51e-09	9606.ENSP00000217407,9606.ENSP00000265983,9606.ENSP00000291744,9606.ENSP00000292609,9606.ENSP00000296280,9606.ENSP00000299367,9606.ENSP00000343445,9606.ENSP00000356037,9606.ENSP00000357156,9606.ENSP00000360522,9606.ENSP00000363079,9606.ENSP00000366109,9606.ENSP00000378131,9606.ENSP00000396688,9606.ENSP00000415941,9606.ENSP00000416561	LBP,HPX,FCN2,PGLYRP2,MASP1,C2,SERPINB4,C4BPA,CD5L,RBP4,MBL2,ANXA1,CFI,C4A,C4B,CFB
GO:0032102	Negative regulation of response to external stimulus	16	387	0.97	1.5	5.15e-09	9606.ENSP00000181383,9606.ENSP00000223642,9606.ENSP00000226218,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000252486,9606.ENSP00000254722,9606.ENSP00000255040,9606.ENSP00000264690,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000308938,9606.ENSP00000343445,9606.ENSP00000377783,9606.ENSP00000389814,9606.ENSP00000493985	CPB2,C5,VTN,LTF,HRG,APOE,SERPINF1,APCS,KLKB1,FGB,F2,PLG,SERPINB4,PROS1,ADIPOQ,KNG1
GO:0051246	Regulation of protein metabolic process	37	2622	0.5	0.83	5.56e-09	9606.ENSP00000181383,9606.ENSP00000215727,9606.ENSP00000223642,9606.ENSP00000226218,9606.ENSP00000230036,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000252486,9606.ENSP00000254722,9606.ENSP00000255040,9606.ENSP00000263598,9606.ENSP00000264690,9606.ENSP00000265132,9606.ENSP00000265983,9606.ENSP00000266041,9606.ENSP00000273283,9606.ENSP00000273784,9606.ENSP00000308541,9606.ENSP00000315130,9606.ENSP00000329374,9606.ENSP00000333203,9606.ENSP00000342850,9606.ENSP00000343445,9606.ENSP00000345179,9606.ENSP00000346839,9606.ENSP00000351190,9606.ENSP00000355627,9606.ENSP00000356037,9606.ENSP00000362924,9606.ENSP00000370473,9606.ENSP00000377783,9606.ENSP00000389814,9606.ENSP00000396688,9606.ENSP00000415769,9606.ENSP00000415941,9606.ENSP00000450540,9606.ENSP00000493985	CPB2,SERPIND1,C5,VTN,GPLD1,LTF,HRG,APOE,SERPINF1,APCS,LCN1,KLKB1,AMBP,HPX,ITIH4,ITIH1,AHSG,F2,CLU,SERPINA7,SERPINA5,SERPINA6,SERPINB4,APOD,FN1,ITIH2,AGT,C4BPA,GSN,IGFBP3,PROS1,ADIPOQ,C4A,ITIH3,C4B,SERPINA3,KNG1
GO:0065009	Regulation of molecular function	40	3085	0.47	0.78	7.25e-09	9606.ENSP00000215727,9606.ENSP00000222381,9606.ENSP00000223642,9606.ENSP00000226218,9606.ENSP00000230036,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000241052,9606.ENSP00000252486,9606.ENSP00000254722,9606.ENSP00000255040,9606.ENSP00000263598,9606.ENSP00000265132,9606.ENSP00000266041,9606.ENSP00000273283,9606.ENSP00000273784,9606.ENSP00000281419,9606.ENSP00000308541,9606.ENSP00000314299,9606.ENSP00000315130,9606.ENSP00000319464,9606.ENSP00000329374,9606.ENSP00000333203,9606.ENSP00000342850,9606.ENSP00000343445,9606.ENSP00000346839,9606.ENSP00000350425,9606.ENSP00000351190,9606.ENSP00000355627,9606.ENSP00000362924,9606.ENSP00000366109,9606.ENSP00000370473,9606.ENSP00000377783,9606.ENSP00000389814,9606.ENSP00000396688,9606.ENSP00000415769,9606.ENSP00000415941,9606.ENSP00000450540,9606.ENSP00000465356,9606.ENSP00000493985	SERPIND1,PON1,C5,VTN,GPLD1,LTF,HRG,CAT,APOE,SERPINF1,APCS,LCN1,AMBP,ITIH4,ITIH1,AHSG,ASAP2,F2,CFHR1,CLU,CPN2,SERPINA7,SERPINA5,SERPINA6,SERPINB4,FN1,APOA4,ITIH2,AGT,GSN,ANXA1,IGFBP3,PROS1,ADIPOQ,C4A,ITIH3,C4B,SERPINA3,APOC1,KNG1
GO:0009892	Negative regulation of metabolic process	39	2982	0.47	0.78	1.15e-08	9606.ENSP00000181383,9606.ENSP00000215727,9606.ENSP00000217407,9606.ENSP00000223642,9606.ENSP00000226218,9606.ENSP00000230036,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000252486,9606.ENSP00000254722,9606.ENSP00000255040,9606.ENSP00000263598,9606.ENSP00000263946,9606.ENSP00000265132,9606.ENSP00000265627,9606.ENSP00000266041,9606.ENSP00000273283,9606.ENSP00000273784,9606.ENSP00000292609,9606.ENSP00000308541,9606.ENSP00000315130,9606.ENSP00000329374,9606.ENSP00000333203,9606.ENSP00000342850,9606.ENSP00000343445,9606.ENSP00000345179,9606.ENSP00000346839,9606.ENSP00000351190,9606.ENSP00000355627,9606.ENSP00000366109,9606.ENSP00000370473,9606.ENSP00000377783,9606.ENSP00000389814,9606.ENSP00000396688,9606.ENSP00000415769,9606.ENSP00000415941,9606.ENSP00000450540,9606.ENSP00000465356,9606.ENSP00000493985	CPB2,SERPIND1,LBP,C5,VTN,GPLD1,LTF,HRG,APOE,SERPINF1,APCS,LCN1,PKP1,AMBP,PON3,ITIH4,ITIH1,AHSG,PGLYRP2,F2,CLU,SERPINA7,SERPINA5,SERPINA6,SERPINB4,APOD,FN1,ITIH2,AGT,ANXA1,IGFBP3,PROS1,ADIPOQ,C4A,ITIH3,C4B,SERPINA3,APOC1,KNG1
GO:0080134	Regulation of response to stress	26	1373	0.63	0.96	3.49e-08	9606.ENSP00000181383,9606.ENSP00000217407,9606.ENSP00000226218,9606.ENSP00000232003,9606.ENSP00000252486,9606.ENSP00000254722,9606.ENSP00000255040,9606.ENSP00000264690,9606.ENSP00000265132,9606.ENSP00000265983,9606.ENSP00000273784,9606.ENSP00000291744,9606.ENSP00000292609,9606.ENSP00000296280,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000308938,9606.ENSP00000315130,9606.ENSP00000343445,9606.ENSP00000355627,9606.ENSP00000363079,9606.ENSP00000366109,9606.ENSP00000377783,9606.ENSP00000378131,9606.ENSP00000389814,9606.ENSP00000493985	CPB2,LBP,VTN,HRG,APOE,SERPINF1,APCS,KLKB1,AMBP,HPX,AHSG,FCN2,PGLYRP2,MASP1,FGB,F2,PLG,CLU,SERPINB4,AGT,MBL2,ANXA1,PROS1,CFI,ADIPOQ,KNG1
GO:0006957	Complement activation, alternative pathway	6	16	1.93	2.04	9.86e-08	9606.ENSP00000223642,9606.ENSP00000263408,9606.ENSP00000322061,9606.ENSP00000354458,9606.ENSP00000360281,9606.ENSP00000416561	C5,C9,C7,C8A,C8B,CFB
GO:0010605	Negative regulation of macromolecule metabolic process	36	2760	0.47	0.75	1.03e-07	9606.ENSP00000181383,9606.ENSP00000215727,9606.ENSP00000217407,9606.ENSP00000223642,9606.ENSP00000226218,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000252486,9606.ENSP00000254722,9606.ENSP00000255040,9606.ENSP00000263598,9606.ENSP00000263946,9606.ENSP00000265132,9606.ENSP00000266041,9606.ENSP00000273283,9606.ENSP00000273784,9606.ENSP00000292609,9606.ENSP00000308541,9606.ENSP00000315130,9606.ENSP00000329374,9606.ENSP00000333203,9606.ENSP00000342850,9606.ENSP00000343445,9606.ENSP00000345179,9606.ENSP00000346839,9606.ENSP00000351190,9606.ENSP00000355627,9606.ENSP00000366109,9606.ENSP00000370473,9606.ENSP00000377783,9606.ENSP00000389814,9606.ENSP00000396688,9606.ENSP00000415769,9606.ENSP00000415941,9606.ENSP00000450540,9606.ENSP00000493985	CPB2,SERPIND1,LBP,C5,VTN,LTF,HRG,APOE,SERPINF1,APCS,LCN1,PKP1,AMBP,ITIH4,ITIH1,AHSG,PGLYRP2,F2,CLU,SERPINA7,SERPINA5,SERPINA6,SERPINB4,APOD,FN1,ITIH2,AGT,ANXA1,IGFBP3,PROS1,ADIPOQ,C4A,ITIH3,C4B,SERPINA3,KNG1
GO:0051050	Positive regulation of transport	21	915	0.72	1.04	1.04e-07	9606.ENSP00000181383,9606.ENSP00000222381,9606.ENSP00000226218,9606.ENSP00000230036,9606.ENSP00000252486,9606.ENSP00000273784,9606.ENSP00000291744,9606.ENSP00000296280,9606.ENSP00000299367,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000315130,9606.ENSP00000355627,9606.ENSP00000360522,9606.ENSP00000363079,9606.ENSP00000366109,9606.ENSP00000389814,9606.ENSP00000396688,9606.ENSP00000415941,9606.ENSP00000416561,9606.ENSP00000417138	CPB2,PON1,VTN,GPLD1,APOE,AHSG,FCN2,MASP1,C2,FGB,F2,CLU,AGT,RBP4,MBL2,ANXA1,ADIPOQ,C4A,C4B,CFB,PLTP
GO:0065007	Biological regulation	80	12385	0.17	0.45	1.18e-07	9606.ENSP00000181383,9606.ENSP00000215727,9606.ENSP00000217407,9606.ENSP00000222381,9606.ENSP00000223642,9606.ENSP00000226218,9606.ENSP00000230036,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000241052,9606.ENSP00000251595,9606.ENSP00000252486,9606.ENSP00000253354,9606.ENSP00000254722,9606.ENSP00000255030,9606.ENSP00000255040,9606.ENSP00000261267,9606.ENSP00000262919,9606.ENSP00000263408,9606.ENSP00000263598,9606.ENSP00000263946,9606.ENSP00000264381,9606.ENSP00000264613,9606.ENSP00000264690,9606.ENSP00000265132,9606.ENSP00000265627,9606.ENSP00000265983,9606.ENSP00000266041,9606.ENSP00000266718,9606.ENSP00000273283,9606.ENSP00000273784,9606.ENSP00000275428,9606.ENSP00000281419,9606.ENSP00000291009,9606.ENSP00000291744,9606.ENSP00000292609,9606.ENSP00000296280,9606.ENSP00000299367,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000308938,9606.ENSP00000314299,9606.ENSP00000315130,9606.ENSP00000319464,9606.ENSP00000322061,9606.ENSP00000329374,9606.ENSP00000333203,9606.ENSP00000342850,9606.ENSP00000343445,9606.ENSP00000345179,9606.ENSP00000346839,9606.ENSP00000350425,9606.ENSP00000351190,9606.ENSP00000354458,9606.ENSP00000355627,9606.ENSP00000356037,9606.ENSP00000357156,9606.ENSP00000360281,9606.ENSP00000360522,9606.ENSP00000360687,9606.ENSP00000362924,9606.ENSP00000363079,9606.ENSP00000363770,9606.ENSP00000365081,9606.ENSP00000366109,9606.ENSP00000370473,9606.ENSP00000377783,9606.ENSP00000378131,9606.ENSP00000385035,9606.ENSP00000389814,9606.ENSP00000396688,9606.ENSP00000415769,9606.ENSP00000415941,9606.ENSP00000416561,9606.ENSP00000416683,9606.ENSP00000417138,9606.ENSP00000440066,9606.ENSP00000450540,9606.ENSP00000465356,9606.ENSP00000493985	CPB2,SERPIND1,LBP,PON1,C5,VTN,GPLD1,LTF,HRG,CAT,HBA2,APOE,BPIFB1,SERPINF1,CRP,APCS,LYZ,ATRN,C9,LCN1,PKP1,BCHE,CP,KLKB1,AMBP,PON3,HPX,ITIH4,LUM,ITIH1,AHSG,GGCT,ASAP2,PIP,FCN2,PGLYRP2,MASP1,C2,FGB,F2,PLG,CFHR1,CLU,CPN2,C7,SERPINA7,SERPINA5,SERPINA6,SERPINB4,APOD,FN1,APOA4,ITIH2,C8A,AGT,C4BPA,CD5L,C8B,RBP4,PTGDS,GSN,MBL2,C1QC,APOM,ANXA1,IGFBP3,PROS1,CFI,C1S,ADIPOQ,C4A,ITIH3,C4B,CFB,IGFALS,PLTP,JCHAIN,SERPINA3,APOC1,KNG1
GO:0051917	Regulation of fibrinolysis	6	18	1.88	1.97	1.67e-07	9606.ENSP00000181383,9606.ENSP00000226218,9606.ENSP00000232003,9606.ENSP00000264690,9606.ENSP00000308541,9606.ENSP00000308938	CPB2,VTN,HRG,KLKB1,F2,PLG
GO:0048585	Negative regulation of response to stimulus	27	1612	0.58	0.86	1.88e-07	9606.ENSP00000181383,9606.ENSP00000223642,9606.ENSP00000226218,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000252486,9606.ENSP00000253354,9606.ENSP00000254722,9606.ENSP00000255040,9606.ENSP00000264690,9606.ENSP00000265132,9606.ENSP00000273784,9606.ENSP00000292609,9606.ENSP00000296280,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000308938,9606.ENSP00000315130,9606.ENSP00000343445,9606.ENSP00000345179,9606.ENSP00000355627,9606.ENSP00000356037,9606.ENSP00000366109,9606.ENSP00000370473,9606.ENSP00000377783,9606.ENSP00000389814,9606.ENSP00000493985	CPB2,C5,VTN,LTF,HRG,APOE,BPIFB1,SERPINF1,APCS,KLKB1,AMBP,AHSG,PGLYRP2,MASP1,FGB,F2,PLG,CLU,SERPINB4,APOD,AGT,C4BPA,ANXA1,IGFBP3,PROS1,ADIPOQ,KNG1
GO:0051172	Negative regulation of nitrogen compound metabolic process	33	2403	0.49	0.76	2.02e-07	9606.ENSP00000181383,9606.ENSP00000215727,9606.ENSP00000223642,9606.ENSP00000226218,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000252486,9606.ENSP00000254722,9606.ENSP00000255040,9606.ENSP00000263598,9606.ENSP00000263946,9606.ENSP00000265132,9606.ENSP00000266041,9606.ENSP00000273283,9606.ENSP00000273784,9606.ENSP00000308541,9606.ENSP00000315130,9606.ENSP00000329374,9606.ENSP00000333203,9606.ENSP00000342850,9606.ENSP00000343445,9606.ENSP00000345179,9606.ENSP00000351190,9606.ENSP00000355627,9606.ENSP00000370473,9606.ENSP00000377783,9606.ENSP00000389814,9606.ENSP00000396688,9606.ENSP00000415769,9606.ENSP00000415941,9606.ENSP00000450540,9606.ENSP00000465356,9606.ENSP00000493985	CPB2,SERPIND1,C5,VTN,LTF,HRG,APOE,SERPINF1,APCS,LCN1,PKP1,AMBP,ITIH4,ITIH1,AHSG,F2,CLU,SERPINA7,SERPINA5,SERPINA6,SERPINB4,APOD,ITIH2,AGT,IGFBP3,PROS1,ADIPOQ,C4A,ITIH3,C4B,SERPINA3,APOC1,KNG1
GO:0050764	Regulation of phagocytosis	9	104	1.29	1.59	3.46e-07	9606.ENSP00000273784,9606.ENSP00000291744,9606.ENSP00000296280,9606.ENSP00000299367,9606.ENSP00000363079,9606.ENSP00000389814,9606.ENSP00000396688,9606.ENSP00000415941,9606.ENSP00000416561	AHSG,FCN2,MASP1,C2,MBL2,ADIPOQ,C4A,C4B,CFB
GO:0051702	Biological process involved in interaction with symbiont	9	108	1.28	1.55	4.66e-07	9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000252486,9606.ENSP00000255040,9606.ENSP00000308541,9606.ENSP00000308938,9606.ENSP00000314299,9606.ENSP00000346839,9606.ENSP00000363079	LTF,HRG,APOE,APCS,F2,PLG,CFHR1,FN1,MBL2
GO:0019835	Cytolysis	6	23	1.77	1.8	5.41e-07	9606.ENSP00000223642,9606.ENSP00000261267,9606.ENSP00000263408,9606.ENSP00000322061,9606.ENSP00000354458,9606.ENSP00000360281	C5,LYZ,C9,C7,C8A,C8B
GO:0008228	Opsonization	5	9	2.1	1.87	5.71e-07	9606.ENSP00000217407,9606.ENSP00000255030,9606.ENSP00000291744,9606.ENSP00000363079,9606.ENSP00000415941	LBP,CRP,FCN2,MBL2,C4B
GO:0050766	Positive regulation of phagocytosis	8	75	1.38	1.6	6.02e-07	9606.ENSP00000273784,9606.ENSP00000291744,9606.ENSP00000296280,9606.ENSP00000299367,9606.ENSP00000363079,9606.ENSP00000396688,9606.ENSP00000415941,9606.ENSP00000416561	AHSG,FCN2,MASP1,C2,MBL2,C4A,C4B,CFB
GO:0007596	Blood coagulation	10	173	1.12	1.33	1.52e-06	9606.ENSP00000181383,9606.ENSP00000215727,9606.ENSP00000232003,9606.ENSP00000264690,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000308938,9606.ENSP00000346839,9606.ENSP00000377783,9606.ENSP00000493985	CPB2,SERPIND1,HRG,KLKB1,FGB,F2,PLG,FN1,PROS1,KNG1
GO:0034369	Plasma lipoprotein particle remodeling	6	29	1.67	1.63	1.70e-06	9606.ENSP00000252486,9606.ENSP00000350425,9606.ENSP00000355627,9606.ENSP00000365081,9606.ENSP00000417138,9606.ENSP00000465356	APOE,APOA4,AGT,APOM,PLTP,APOC1
GO:0097006	Regulation of plasma lipoprotein particle levels	7	54	1.47	1.55	1.70e-06	9606.ENSP00000252486,9606.ENSP00000350425,9606.ENSP00000355627,9606.ENSP00000365081,9606.ENSP00000389814,9606.ENSP00000417138,9606.ENSP00000465356	APOE,APOA4,AGT,APOM,ADIPOQ,PLTP,APOC1
GO:0050789	Regulation of biological process	76	11655	0.17	0.43	1.73e-06	9606.ENSP00000181383,9606.ENSP00000215727,9606.ENSP00000217407,9606.ENSP00000222381,9606.ENSP00000223642,9606.ENSP00000226218,9606.ENSP00000230036,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000241052,9606.ENSP00000251595,9606.ENSP00000252486,9606.ENSP00000253354,9606.ENSP00000254722,9606.ENSP00000255030,9606.ENSP00000255040,9606.ENSP00000262919,9606.ENSP00000263408,9606.ENSP00000263598,9606.ENSP00000263946,9606.ENSP00000264381,9606.ENSP00000264690,9606.ENSP00000265132,9606.ENSP00000265627,9606.ENSP00000265983,9606.ENSP00000266041,9606.ENSP00000266718,9606.ENSP00000273283,9606.ENSP00000273784,9606.ENSP00000275428,9606.ENSP00000291009,9606.ENSP00000291744,9606.ENSP00000292609,9606.ENSP00000296280,9606.ENSP00000299367,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000308938,9606.ENSP00000314299,9606.ENSP00000315130,9606.ENSP00000322061,9606.ENSP00000329374,9606.ENSP00000333203,9606.ENSP00000342850,9606.ENSP00000343445,9606.ENSP00000345179,9606.ENSP00000346839,9606.ENSP00000350425,9606.ENSP00000351190,9606.ENSP00000354458,9606.ENSP00000355627,9606.ENSP00000356037,9606.ENSP00000357156,9606.ENSP00000360281,9606.ENSP00000360522,9606.ENSP00000360687,9606.ENSP00000362924,9606.ENSP00000363079,9606.ENSP00000363770,9606.ENSP00000365081,9606.ENSP00000366109,9606.ENSP00000370473,9606.ENSP00000377783,9606.ENSP00000378131,9606.ENSP00000385035,9606.ENSP00000389814,9606.ENSP00000396688,9606.ENSP00000415769,9606.ENSP00000415941,9606.ENSP00000416561,9606.ENSP00000416683,9606.ENSP00000417138,9606.ENSP00000440066,9606.ENSP00000450540,9606.ENSP00000465356,9606.ENSP00000493985	CPB2,SERPIND1,LBP,PON1,C5,VTN,GPLD1,LTF,HRG,CAT,HBA2,APOE,BPIFB1,SERPINF1,CRP,APCS,ATRN,C9,LCN1,PKP1,BCHE,KLKB1,AMBP,PON3,HPX,ITIH4,LUM,ITIH1,AHSG,GGCT,PIP,FCN2,PGLYRP2,MASP1,C2,FGB,F2,PLG,CFHR1,CLU,C7,SERPINA7,SERPINA5,SERPINA6,SERPINB4,APOD,FN1,APOA4,ITIH2,C8A,AGT,C4BPA,CD5L,C8B,RBP4,PTGDS,GSN,MBL2,C1QC,APOM,ANXA1,IGFBP3,PROS1,CFI,C1S,ADIPOQ,C4A,ITIH3,C4B,CFB,IGFALS,PLTP,JCHAIN,SERPINA3,APOC1,KNG1
GO:0051918	Negative regulation of fibrinolysis	5	13	1.94	1.67	2.16e-06	9606.ENSP00000181383,9606.ENSP00000226218,9606.ENSP00000232003,9606.ENSP00000308541,9606.ENSP00000308938	CPB2,VTN,HRG,F2,PLG
GO:0031347	Regulation of defense response	16	638	0.75	0.95	3.99e-06	9606.ENSP00000217407,9606.ENSP00000252486,9606.ENSP00000254722,9606.ENSP00000255040,9606.ENSP00000264690,9606.ENSP00000265983,9606.ENSP00000273784,9606.ENSP00000291744,9606.ENSP00000292609,9606.ENSP00000296280,9606.ENSP00000343445,9606.ENSP00000355627,9606.ENSP00000363079,9606.ENSP00000366109,9606.ENSP00000378131,9606.ENSP00000389814	LBP,APOE,SERPINF1,APCS,KLKB1,HPX,AHSG,FCN2,PGLYRP2,MASP1,SERPINB4,AGT,MBL2,ANXA1,CFI,ADIPOQ
GO:0060627	Regulation of vesicle-mediated transport	15	551	0.79	0.98	4.01e-06	9606.ENSP00000226218,9606.ENSP00000252486,9606.ENSP00000273784,9606.ENSP00000291744,9606.ENSP00000296280,9606.ENSP00000299367,9606.ENSP00000306099,9606.ENSP00000315130,9606.ENSP00000363079,9606.ENSP00000366109,9606.ENSP00000389814,9606.ENSP00000396688,9606.ENSP00000415941,9606.ENSP00000416561,9606.ENSP00000465356	VTN,APOE,AHSG,FCN2,MASP1,C2,FGB,CLU,MBL2,ANXA1,ADIPOQ,C4A,C4B,CFB,APOC1
GO:0051239	Regulation of multicellular organismal process	33	2749	0.43	0.64	4.77e-06	9606.ENSP00000181383,9606.ENSP00000217407,9606.ENSP00000223642,9606.ENSP00000226218,9606.ENSP00000230036,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000252486,9606.ENSP00000254722,9606.ENSP00000255030,9606.ENSP00000255040,9606.ENSP00000262919,9606.ENSP00000264690,9606.ENSP00000266718,9606.ENSP00000273784,9606.ENSP00000292609,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000308938,9606.ENSP00000315130,9606.ENSP00000345179,9606.ENSP00000346839,9606.ENSP00000350425,9606.ENSP00000355627,9606.ENSP00000360522,9606.ENSP00000360687,9606.ENSP00000363770,9606.ENSP00000365081,9606.ENSP00000366109,9606.ENSP00000377783,9606.ENSP00000389814,9606.ENSP00000465356,9606.ENSP00000493985	CPB2,LBP,C5,VTN,GPLD1,LTF,HRG,APOE,SERPINF1,CRP,APCS,ATRN,KLKB1,LUM,AHSG,PGLYRP2,FGB,F2,PLG,CLU,APOD,FN1,APOA4,AGT,RBP4,PTGDS,C1QC,APOM,ANXA1,PROS1,ADIPOQ,APOC1,KNG1
GO:0034375	High-density lipoprotein particle remodeling	5	16	1.85	1.56	4.80e-06	9606.ENSP00000252486,9606.ENSP00000350425,9606.ENSP00000365081,9606.ENSP00000417138,9606.ENSP00000465356	APOE,APOA4,APOM,PLTP,APOC1
GO:0002699	Positive regulation of immune effector process	11	264	0.97	1.13	5.68e-06	9606.ENSP00000217407,9606.ENSP00000265983,9606.ENSP00000291744,9606.ENSP00000296280,9606.ENSP00000299367,9606.ENSP00000360522,9606.ENSP00000363079,9606.ENSP00000366109,9606.ENSP00000396688,9606.ENSP00000415941,9606.ENSP00000416561	LBP,HPX,FCN2,MASP1,C2,RBP4,MBL2,ANXA1,C4A,C4B,CFB
GO:0048518	Positive regulation of biological process	52	6207	0.28	0.5	9.48e-06	9606.ENSP00000181383,9606.ENSP00000217407,9606.ENSP00000222381,9606.ENSP00000223642,9606.ENSP00000226218,9606.ENSP00000230036,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000241052,9606.ENSP00000251595,9606.ENSP00000252486,9606.ENSP00000254722,9606.ENSP00000255030,9606.ENSP00000263408,9606.ENSP00000263946,9606.ENSP00000264690,9606.ENSP00000265983,9606.ENSP00000266718,9606.ENSP00000273784,9606.ENSP00000291009,9606.ENSP00000291744,9606.ENSP00000296280,9606.ENSP00000299367,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000308938,9606.ENSP00000314299,9606.ENSP00000315130,9606.ENSP00000322061,9606.ENSP00000346839,9606.ENSP00000350425,9606.ENSP00000354458,9606.ENSP00000355627,9606.ENSP00000356037,9606.ENSP00000357156,9606.ENSP00000360281,9606.ENSP00000360522,9606.ENSP00000362924,9606.ENSP00000363079,9606.ENSP00000363770,9606.ENSP00000366109,9606.ENSP00000370473,9606.ENSP00000378131,9606.ENSP00000385035,9606.ENSP00000389814,9606.ENSP00000396688,9606.ENSP00000415941,9606.ENSP00000416561,9606.ENSP00000417138,9606.ENSP00000440066,9606.ENSP00000465356,9606.ENSP00000493985	CPB2,LBP,PON1,C5,VTN,GPLD1,LTF,HRG,CAT,HBA2,APOE,SERPINF1,CRP,C9,PKP1,KLKB1,HPX,LUM,AHSG,PIP,FCN2,MASP1,C2,FGB,F2,PLG,CFHR1,CLU,C7,FN1,APOA4,C8A,AGT,C4BPA,CD5L,C8B,RBP4,GSN,MBL2,C1QC,ANXA1,IGFBP3,CFI,C1S,ADIPOQ,C4A,C4B,CFB,PLTP,JCHAIN,APOC1,KNG1
GO:0050878	Regulation of body fluid levels	12	371	0.86	0.97	1.81e-05	9606.ENSP00000181383,9606.ENSP00000215727,9606.ENSP00000226218,9606.ENSP00000232003,9606.ENSP00000252486,9606.ENSP00000264690,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000308938,9606.ENSP00000346839,9606.ENSP00000377783,9606.ENSP00000493985	CPB2,SERPIND1,VTN,HRG,APOE,KLKB1,FGB,F2,PLG,FN1,PROS1,KNG1
GO:0009617	Response to bacterium	15	663	0.71	0.81	3.86e-05	9606.ENSP00000217407,9606.ENSP00000231751,9606.ENSP00000255030,9606.ENSP00000261267,9606.ENSP00000291744,9606.ENSP00000292609,9606.ENSP00000299367,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000356037,9606.ENSP00000363079,9606.ENSP00000389814,9606.ENSP00000415941,9606.ENSP00000416561,9606.ENSP00000440066	LBP,LTF,CRP,LYZ,FCN2,PGLYRP2,C2,FGB,F2,C4BPA,MBL2,ADIPOQ,C4B,CFB,JCHAIN
GO:0044403	Biological process involved in symbiotic interaction	10	257	0.94	0.97	4.30e-05	9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000252486,9606.ENSP00000255040,9606.ENSP00000292609,9606.ENSP00000308541,9606.ENSP00000308938,9606.ENSP00000314299,9606.ENSP00000346839,9606.ENSP00000363079	LTF,HRG,APOE,APCS,PGLYRP2,F2,PLG,CFHR1,FN1,MBL2
GO:0006869	Lipid transport	11	329	0.88	0.92	4.50e-05	9606.ENSP00000217407,9606.ENSP00000252486,9606.ENSP00000315130,9606.ENSP00000333203,9606.ENSP00000345179,9606.ENSP00000350425,9606.ENSP00000360522,9606.ENSP00000365081,9606.ENSP00000366109,9606.ENSP00000417138,9606.ENSP00000465356	LBP,APOE,CLU,SERPINA5,APOD,APOA4,RBP4,APOM,ANXA1,PLTP,APOC1
GO:0006508	Proteolysis	20	1247	0.56	0.67	6.69e-05	9606.ENSP00000181383,9606.ENSP00000222482,9606.ENSP00000231751,9606.ENSP00000261714,9606.ENSP00000263598,9606.ENSP00000264381,9606.ENSP00000264690,9606.ENSP00000277903,9606.ENSP00000291009,9606.ENSP00000291744,9606.ENSP00000296280,9606.ENSP00000299367,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000308938,9606.ENSP00000357156,9606.ENSP00000363079,9606.ENSP00000378131,9606.ENSP00000385035,9606.ENSP00000416561	CPB2,CPA4,LTF,BLMH,LCN1,BCHE,KLKB1,HABP2,PIP,FCN2,MASP1,C2,FGB,F2,PLG,CD5L,MBL2,CFI,C1S,CFB
GO:0090303	Positive regulation of wound healing	6	60	1.35	1.13	6.69e-05	9606.ENSP00000181383,9606.ENSP00000226218,9606.ENSP00000232003,9606.ENSP00000308541,9606.ENSP00000308938,9606.ENSP00000366109	CPB2,VTN,HRG,F2,PLG,ANXA1
GO:0051049	Regulation of transport	24	1763	0.49	0.62	6.94e-05	9606.ENSP00000181383,9606.ENSP00000222381,9606.ENSP00000226218,9606.ENSP00000230036,9606.ENSP00000252486,9606.ENSP00000273784,9606.ENSP00000291744,9606.ENSP00000296280,9606.ENSP00000299367,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000315130,9606.ENSP00000345179,9606.ENSP00000350425,9606.ENSP00000355627,9606.ENSP00000360522,9606.ENSP00000363079,9606.ENSP00000366109,9606.ENSP00000389814,9606.ENSP00000396688,9606.ENSP00000415941,9606.ENSP00000416561,9606.ENSP00000417138,9606.ENSP00000465356	CPB2,PON1,VTN,GPLD1,APOE,AHSG,FCN2,MASP1,C2,FGB,F2,CLU,APOD,APOA4,AGT,RBP4,MBL2,ANXA1,ADIPOQ,C4A,C4B,CFB,PLTP,APOC1
GO:0002683	Negative regulation of immune system process	12	433	0.8	0.83	8.17e-05	9606.ENSP00000223642,9606.ENSP00000231751,9606.ENSP00000255040,9606.ENSP00000265132,9606.ENSP00000292609,9606.ENSP00000296280,9606.ENSP00000343445,9606.ENSP00000345179,9606.ENSP00000356037,9606.ENSP00000363770,9606.ENSP00000366109,9606.ENSP00000389814	C5,LTF,APCS,AMBP,PGLYRP2,MASP1,SERPINB4,APOD,C4BPA,C1QC,ANXA1,ADIPOQ
GO:0032374	Regulation of cholesterol transport	6	64	1.33	1.09	9.22e-05	9606.ENSP00000222381,9606.ENSP00000252486,9606.ENSP00000350425,9606.ENSP00000389814,9606.ENSP00000417138,9606.ENSP00000465356	PON1,APOE,APOA4,ADIPOQ,PLTP,APOC1
GO:0009611	Response to wounding	12	444	0.79	0.81	0.00010	9606.ENSP00000181383,9606.ENSP00000215727,9606.ENSP00000232003,9606.ENSP00000264690,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000308938,9606.ENSP00000345179,9606.ENSP00000346839,9606.ENSP00000350425,9606.ENSP00000377783,9606.ENSP00000493985	CPB2,SERPIND1,HRG,KLKB1,FGB,F2,PLG,APOD,FN1,APOA4,PROS1,KNG1
GO:0032879	Regulation of localization	26	2103	0.45	0.57	0.00012	9606.ENSP00000181383,9606.ENSP00000222381,9606.ENSP00000226218,9606.ENSP00000230036,9606.ENSP00000252486,9606.ENSP00000255030,9606.ENSP00000273784,9606.ENSP00000291744,9606.ENSP00000296280,9606.ENSP00000299367,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000315130,9606.ENSP00000345179,9606.ENSP00000350425,9606.ENSP00000355627,9606.ENSP00000360522,9606.ENSP00000362924,9606.ENSP00000363079,9606.ENSP00000366109,9606.ENSP00000389814,9606.ENSP00000396688,9606.ENSP00000415941,9606.ENSP00000416561,9606.ENSP00000417138,9606.ENSP00000465356	CPB2,PON1,VTN,GPLD1,APOE,CRP,AHSG,FCN2,MASP1,C2,FGB,F2,CLU,APOD,APOA4,AGT,RBP4,GSN,MBL2,ANXA1,ADIPOQ,C4A,C4B,CFB,PLTP,APOC1
GO:0009636	Response to toxic substance	9	229	0.95	0.89	0.00014	9606.ENSP00000222381,9606.ENSP00000241052,9606.ENSP00000251595,9606.ENSP00000252486,9606.ENSP00000261714,9606.ENSP00000265132,9606.ENSP00000265627,9606.ENSP00000350425,9606.ENSP00000365081	PON1,CAT,HBA2,APOE,BLMH,AMBP,PON3,APOA4,APOM
GO:1905952	Regulation of lipid localization	8	167	1.04	0.93	0.00014	9606.ENSP00000222381,9606.ENSP00000252486,9606.ENSP00000255030,9606.ENSP00000350425,9606.ENSP00000355627,9606.ENSP00000389814,9606.ENSP00000417138,9606.ENSP00000465356	PON1,APOE,CRP,APOA4,AGT,ADIPOQ,PLTP,APOC1
GO:0042742	Defense response to bacterium	10	306	0.87	0.83	0.00017	9606.ENSP00000217407,9606.ENSP00000231751,9606.ENSP00000255030,9606.ENSP00000261267,9606.ENSP00000291744,9606.ENSP00000292609,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000363079,9606.ENSP00000440066	LBP,LTF,CRP,LYZ,FCN2,PGLYRP2,FGB,F2,MBL2,JCHAIN
GO:0015918	Sterol transport	6	82	1.22	0.93	0.00032	9606.ENSP00000252486,9606.ENSP00000315130,9606.ENSP00000350425,9606.ENSP00000365081,9606.ENSP00000417138,9606.ENSP00000465356	APOE,CLU,APOA4,APOM,PLTP,APOC1
GO:0043691	Reverse cholesterol transport	4	18	1.7	1.03	0.00032	9606.ENSP00000252486,9606.ENSP00000315130,9606.ENSP00000350425,9606.ENSP00000365081	APOE,CLU,APOA4,APOM
GO:0050830	Defense response to Gram-positive bacterium	7	130	1.09	0.88	0.00032	9606.ENSP00000217407,9606.ENSP00000231751,9606.ENSP00000255030,9606.ENSP00000261267,9606.ENSP00000291744,9606.ENSP00000292609,9606.ENSP00000363079	LBP,LTF,CRP,LYZ,FCN2,PGLYRP2,MBL2
GO:0002920	Regulation of humoral immune response	5	46	1.39	0.96	0.00038	9606.ENSP00000265983,9606.ENSP00000296280,9606.ENSP00000356037,9606.ENSP00000357156,9606.ENSP00000378131	HPX,MASP1,C4BPA,CD5L,CFI
GO:0032368	Regulation of lipid transport	7	139	1.06	0.84	0.00047	9606.ENSP00000222381,9606.ENSP00000252486,9606.ENSP00000350425,9606.ENSP00000355627,9606.ENSP00000389814,9606.ENSP00000417138,9606.ENSP00000465356	PON1,APOE,APOA4,AGT,ADIPOQ,PLTP,APOC1
GO:0098869	Cellular oxidant detoxification	6	91	1.17	0.86	0.00056	9606.ENSP00000241052,9606.ENSP00000251595,9606.ENSP00000252486,9606.ENSP00000265132,9606.ENSP00000350425,9606.ENSP00000365081	CAT,HBA2,APOE,AMBP,APOA4,APOM
GO:0030449	Regulation of complement activation	4	22	1.61	0.94	0.00061	9606.ENSP00000296280,9606.ENSP00000356037,9606.ENSP00000357156,9606.ENSP00000378131	MASP1,C4BPA,CD5L,CFI
GO:0002831	Regulation of response to biotic stimulus	10	361	0.8	0.7	0.00066	9606.ENSP00000217407,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000252486,9606.ENSP00000265983,9606.ENSP00000291744,9606.ENSP00000296280,9606.ENSP00000343445,9606.ENSP00000363079,9606.ENSP00000378131	LBP,LTF,HRG,APOE,HPX,FCN2,MASP1,SERPINB4,MBL2,CFI
GO:0019730	Antimicrobial humoral response	7	149	1.03	0.79	0.00071	9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000261267,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000440066,9606.ENSP00000493985	LTF,HRG,LYZ,FGB,F2,JCHAIN,KNG1
GO:0030212	Hyaluronan metabolic process	4	23	1.6	0.92	0.00071	9606.ENSP00000266041,9606.ENSP00000273283,9606.ENSP00000351190,9606.ENSP00000415769	ITIH4,ITIH1,ITIH2,ITIH3
GO:0034377	Plasma lipoprotein particle assembly	4	23	1.6	0.92	0.00071	9606.ENSP00000252486,9606.ENSP00000350425,9606.ENSP00000365081,9606.ENSP00000465356	APOE,APOA4,APOM,APOC1
GO:0032103	Positive regulation of response to external stimulus	11	453	0.74	0.67	0.00072	9606.ENSP00000181383,9606.ENSP00000217407,9606.ENSP00000226218,9606.ENSP00000232003,9606.ENSP00000265983,9606.ENSP00000291744,9606.ENSP00000296280,9606.ENSP00000308541,9606.ENSP00000308938,9606.ENSP00000355627,9606.ENSP00000363079	CPB2,LBP,VTN,HRG,HPX,FCN2,MASP1,F2,PLG,AGT,MBL2
GO:0006979	Response to oxidative stress	10	368	0.79	0.69	0.00075	9606.ENSP00000241052,9606.ENSP00000251595,9606.ENSP00000252486,9606.ENSP00000262919,9606.ENSP00000265132,9606.ENSP00000345179,9606.ENSP00000350425,9606.ENSP00000363079,9606.ENSP00000366109,9606.ENSP00000389814	CAT,HBA2,APOE,ATRN,AMBP,APOD,APOA4,MBL2,ANXA1,ADIPOQ
GO:0034381	Plasma lipoprotein particle clearance	4	24	1.58	0.9	0.00079	9606.ENSP00000252486,9606.ENSP00000365081,9606.ENSP00000389814,9606.ENSP00000465356	APOE,APOM,ADIPOQ,APOC1
GO:0050727	Regulation of inflammatory response	10	371	0.79	0.68	0.00079	9606.ENSP00000217407,9606.ENSP00000252486,9606.ENSP00000254722,9606.ENSP00000255040,9606.ENSP00000264690,9606.ENSP00000273784,9606.ENSP00000292609,9606.ENSP00000355627,9606.ENSP00000366109,9606.ENSP00000389814	LBP,APOE,SERPINF1,APCS,KLKB1,AHSG,PGLYRP2,AGT,ANXA1,ADIPOQ
GO:0065008	Regulation of biological quality	34	3654	0.32	0.44	0.00079	9606.ENSP00000181383,9606.ENSP00000215727,9606.ENSP00000226218,9606.ENSP00000230036,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000252486,9606.ENSP00000254722,9606.ENSP00000255030,9606.ENSP00000261267,9606.ENSP00000263598,9606.ENSP00000264381,9606.ENSP00000264613,9606.ENSP00000264690,9606.ENSP00000265983,9606.ENSP00000291009,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000308938,9606.ENSP00000315130,9606.ENSP00000319464,9606.ENSP00000329374,9606.ENSP00000346839,9606.ENSP00000350425,9606.ENSP00000355627,9606.ENSP00000360522,9606.ENSP00000362924,9606.ENSP00000365081,9606.ENSP00000366109,9606.ENSP00000377783,9606.ENSP00000389814,9606.ENSP00000440066,9606.ENSP00000450540,9606.ENSP00000493985	CPB2,SERPIND1,VTN,GPLD1,LTF,HRG,APOE,SERPINF1,CRP,LYZ,LCN1,BCHE,CP,KLKB1,HPX,PIP,FGB,F2,PLG,CLU,CPN2,SERPINA7,FN1,APOA4,AGT,RBP4,GSN,APOM,ANXA1,PROS1,ADIPOQ,JCHAIN,SERPINA3,KNG1
GO:0072378	Blood coagulation, fibrin clot formation	4	24	1.58	0.9	0.00079	9606.ENSP00000264690,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000346839	KLKB1,FGB,F2,FN1
GO:0045834	Positive regulation of lipid metabolic process	7	155	1.01	0.77	0.00085	9606.ENSP00000230036,9606.ENSP00000252486,9606.ENSP00000308541,9606.ENSP00000350425,9606.ENSP00000366109,9606.ENSP00000389814,9606.ENSP00000465356	GPLD1,APOE,F2,APOA4,ANXA1,ADIPOQ,APOC1
GO:0010875	Positive regulation of cholesterol efflux	4	26	1.54	0.87	0.0010	9606.ENSP00000222381,9606.ENSP00000252486,9606.ENSP00000389814,9606.ENSP00000417138	PON1,APOE,ADIPOQ,PLTP
GO:0015850	Organic hydroxy compound transport	7	163	0.99	0.74	0.0011	9606.ENSP00000252486,9606.ENSP00000315130,9606.ENSP00000350425,9606.ENSP00000360522,9606.ENSP00000365081,9606.ENSP00000417138,9606.ENSP00000465356	APOE,CLU,APOA4,RBP4,APOM,PLTP,APOC1
GO:0019222	Regulation of metabolic process	50	6784	0.22	0.38	0.0011	9606.ENSP00000181383,9606.ENSP00000215727,9606.ENSP00000217407,9606.ENSP00000223642,9606.ENSP00000226218,9606.ENSP00000230036,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000241052,9606.ENSP00000252486,9606.ENSP00000254722,9606.ENSP00000255030,9606.ENSP00000255040,9606.ENSP00000263598,9606.ENSP00000263946,9606.ENSP00000264690,9606.ENSP00000265132,9606.ENSP00000265627,9606.ENSP00000265983,9606.ENSP00000266041,9606.ENSP00000266718,9606.ENSP00000273283,9606.ENSP00000273784,9606.ENSP00000291009,9606.ENSP00000292609,9606.ENSP00000308541,9606.ENSP00000315130,9606.ENSP00000329374,9606.ENSP00000333203,9606.ENSP00000342850,9606.ENSP00000343445,9606.ENSP00000345179,9606.ENSP00000346839,9606.ENSP00000350425,9606.ENSP00000351190,9606.ENSP00000355627,9606.ENSP00000356037,9606.ENSP00000360522,9606.ENSP00000362924,9606.ENSP00000366109,9606.ENSP00000370473,9606.ENSP00000377783,9606.ENSP00000389814,9606.ENSP00000396688,9606.ENSP00000415769,9606.ENSP00000415941,9606.ENSP00000440066,9606.ENSP00000450540,9606.ENSP00000465356,9606.ENSP00000493985	CPB2,SERPIND1,LBP,C5,VTN,GPLD1,LTF,HRG,CAT,APOE,SERPINF1,CRP,APCS,LCN1,PKP1,KLKB1,AMBP,PON3,HPX,ITIH4,LUM,ITIH1,AHSG,PIP,PGLYRP2,F2,CLU,SERPINA7,SERPINA5,SERPINA6,SERPINB4,APOD,FN1,APOA4,ITIH2,AGT,C4BPA,RBP4,GSN,ANXA1,IGFBP3,PROS1,ADIPOQ,C4A,ITIH3,C4B,JCHAIN,SERPINA3,APOC1,KNG1
GO:0033344	Cholesterol efflux	4	27	1.53	0.86	0.0011	9606.ENSP00000252486,9606.ENSP00000350425,9606.ENSP00000365081,9606.ENSP00000465356	APOE,APOA4,APOM,APOC1
GO:0042592	Homeostatic process	19	1406	0.49	0.51	0.0012	9606.ENSP00000181383,9606.ENSP00000231751,9606.ENSP00000252486,9606.ENSP00000254722,9606.ENSP00000261267,9606.ENSP00000263598,9606.ENSP00000264613,9606.ENSP00000265983,9606.ENSP00000291009,9606.ENSP00000308541,9606.ENSP00000308938,9606.ENSP00000350425,9606.ENSP00000355627,9606.ENSP00000360522,9606.ENSP00000365081,9606.ENSP00000366109,9606.ENSP00000389814,9606.ENSP00000440066,9606.ENSP00000450540	CPB2,LTF,APOE,SERPINF1,LYZ,LCN1,CP,HPX,PIP,F2,PLG,APOA4,AGT,RBP4,APOM,ANXA1,ADIPOQ,JCHAIN,SERPINA3
GO:1902106	Negative regulation of leukocyte differentiation	6	107	1.1	0.77	0.0012	9606.ENSP00000231751,9606.ENSP00000255040,9606.ENSP00000292609,9606.ENSP00000363770,9606.ENSP00000366109,9606.ENSP00000389814	LTF,APCS,PGLYRP2,C1QC,ANXA1,ADIPOQ
GO:0000302	Response to reactive oxygen species	7	169	0.97	0.71	0.0014	9606.ENSP00000241052,9606.ENSP00000251595,9606.ENSP00000252486,9606.ENSP00000265132,9606.ENSP00000345179,9606.ENSP00000350425,9606.ENSP00000366109	CAT,HBA2,APOE,AMBP,APOD,APOA4,ANXA1
GO:0010594	Regulation of endothelial cell migration	7	169	0.97	0.71	0.0014	9606.ENSP00000230036,9606.ENSP00000232003,9606.ENSP00000252486,9606.ENSP00000254722,9606.ENSP00000308938,9606.ENSP00000355627,9606.ENSP00000366109	GPLD1,HRG,APOE,SERPINF1,PLG,AGT,ANXA1
GO:0030301	Cholesterol transport	5	65	1.24	0.78	0.0014	9606.ENSP00000252486,9606.ENSP00000315130,9606.ENSP00000350425,9606.ENSP00000365081,9606.ENSP00000465356	APOE,CLU,APOA4,APOM,APOC1
GO:0045088	Regulation of innate immune response	8	238	0.88	0.68	0.0014	9606.ENSP00000217407,9606.ENSP00000252486,9606.ENSP00000265983,9606.ENSP00000291744,9606.ENSP00000296280,9606.ENSP00000343445,9606.ENSP00000363079,9606.ENSP00000378131	LBP,APOE,HPX,FCN2,MASP1,SERPINB4,MBL2,CFI
GO:0051873	Killing by host of symbiont cells	4	29	1.49	0.83	0.0014	9606.ENSP00000232003,9606.ENSP00000308541,9606.ENSP00000314299,9606.ENSP00000363079	HRG,F2,CFHR1,MBL2
GO:1905920	Positive regulation of CoA-transferase activity	3	8	1.93	0.86	0.0014	9606.ENSP00000252486,9606.ENSP00000350425,9606.ENSP00000355627	APOE,APOA4,AGT
GO:2000427	Positive regulation of apoptotic cell clearance	3	8	1.93	0.86	0.0014	9606.ENSP00000299367,9606.ENSP00000396688,9606.ENSP00000415941	C2,C4A,C4B
GO:0008285	Negative regulation of cell population proliferation	13	713	0.62	0.56	0.0017	9606.ENSP00000181383,9606.ENSP00000230036,9606.ENSP00000232003,9606.ENSP00000252486,9606.ENSP00000254722,9606.ENSP00000255030,9606.ENSP00000264381,9606.ENSP00000308938,9606.ENSP00000345179,9606.ENSP00000360522,9606.ENSP00000360687,9606.ENSP00000370473,9606.ENSP00000389814	CPB2,GPLD1,HRG,APOE,SERPINF1,CRP,BCHE,PLG,APOD,RBP4,PTGDS,IGFBP3,ADIPOQ
GO:0002752	Cell surface pattern recognition receptor signaling pathway	3	9	1.88	0.83	0.0018	9606.ENSP00000291744,9606.ENSP00000296280,9606.ENSP00000363079	FCN2,MASP1,MBL2
GO:0001817	Regulation of cytokine production	13	739	0.6	0.53	0.0023	9606.ENSP00000217407,9606.ENSP00000223642,9606.ENSP00000231751,9606.ENSP00000255030,9606.ENSP00000266718,9606.ENSP00000292609,9606.ENSP00000308541,9606.ENSP00000315130,9606.ENSP00000345179,9606.ENSP00000346839,9606.ENSP00000355627,9606.ENSP00000366109,9606.ENSP00000389814	LBP,C5,LTF,CRP,LUM,PGLYRP2,F2,CLU,APOD,FN1,AGT,ANXA1,ADIPOQ
GO:0001867	Complement activation, lectin pathway	3	10	1.83	0.8	0.0023	9606.ENSP00000291744,9606.ENSP00000296280,9606.ENSP00000363079	FCN2,MASP1,MBL2
GO:0019216	Regulation of lipid metabolic process	9	346	0.77	0.59	0.0026	9606.ENSP00000230036,9606.ENSP00000252486,9606.ENSP00000308541,9606.ENSP00000345179,9606.ENSP00000350425,9606.ENSP00000366109,9606.ENSP00000389814,9606.ENSP00000450540,9606.ENSP00000465356	GPLD1,APOE,F2,APOD,APOA4,ANXA1,ADIPOQ,SERPINA3,APOC1
GO:0020027	Hemoglobin metabolic process	3	11	1.79	0.77	0.0028	9606.ENSP00000241052,9606.ENSP00000265132,9606.ENSP00000265983	CAT,AMBP,HPX
GO:0001895	Retina homeostasis	5	78	1.16	0.68	0.0031	9606.ENSP00000231751,9606.ENSP00000261267,9606.ENSP00000263598,9606.ENSP00000291009,9606.ENSP00000440066	LTF,LYZ,LCN1,PIP,JCHAIN
GO:0033700	Phospholipid efflux	3	12	1.75	0.74	0.0034	9606.ENSP00000252486,9606.ENSP00000350425,9606.ENSP00000465356	APOE,APOA4,APOC1
GO:0034380	High-density lipoprotein particle assembly	3	12	1.75	0.74	0.0034	9606.ENSP00000252486,9606.ENSP00000350425,9606.ENSP00000365081	APOE,APOA4,APOM
GO:0051838	Cytolysis by host of symbiont cells	3	12	1.75	0.74	0.0034	9606.ENSP00000232003,9606.ENSP00000308541,9606.ENSP00000314299	HRG,F2,CFHR1
GO:0060255	Regulation of macromolecule metabolic process	46	6249	0.22	0.35	0.0034	9606.ENSP00000181383,9606.ENSP00000215727,9606.ENSP00000217407,9606.ENSP00000223642,9606.ENSP00000226218,9606.ENSP00000230036,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000241052,9606.ENSP00000252486,9606.ENSP00000254722,9606.ENSP00000255030,9606.ENSP00000255040,9606.ENSP00000263598,9606.ENSP00000263946,9606.ENSP00000264690,9606.ENSP00000265132,9606.ENSP00000265983,9606.ENSP00000266041,9606.ENSP00000266718,9606.ENSP00000273283,9606.ENSP00000273784,9606.ENSP00000291009,9606.ENSP00000292609,9606.ENSP00000308541,9606.ENSP00000315130,9606.ENSP00000329374,9606.ENSP00000333203,9606.ENSP00000342850,9606.ENSP00000343445,9606.ENSP00000345179,9606.ENSP00000346839,9606.ENSP00000351190,9606.ENSP00000355627,9606.ENSP00000356037,9606.ENSP00000360522,9606.ENSP00000362924,9606.ENSP00000366109,9606.ENSP00000370473,9606.ENSP00000377783,9606.ENSP00000389814,9606.ENSP00000396688,9606.ENSP00000415769,9606.ENSP00000415941,9606.ENSP00000450540,9606.ENSP00000493985	CPB2,SERPIND1,LBP,C5,VTN,GPLD1,LTF,HRG,CAT,APOE,SERPINF1,CRP,APCS,LCN1,PKP1,KLKB1,AMBP,HPX,ITIH4,LUM,ITIH1,AHSG,PIP,PGLYRP2,F2,CLU,SERPINA7,SERPINA5,SERPINA6,SERPINB4,APOD,FN1,ITIH2,AGT,C4BPA,RBP4,GSN,ANXA1,IGFBP3,PROS1,ADIPOQ,C4A,ITIH3,C4B,SERPINA3,KNG1
GO:0001818	Negative regulation of cytokine production	8	284	0.8	0.57	0.0040	9606.ENSP00000217407,9606.ENSP00000231751,9606.ENSP00000292609,9606.ENSP00000308541,9606.ENSP00000345179,9606.ENSP00000346839,9606.ENSP00000366109,9606.ENSP00000389814	LBP,LTF,PGLYRP2,F2,APOD,FN1,ANXA1,ADIPOQ
GO:0030334	Regulation of cell migration	14	927	0.53	0.46	0.0053	9606.ENSP00000217407,9606.ENSP00000223642,9606.ENSP00000226218,9606.ENSP00000230036,9606.ENSP00000232003,9606.ENSP00000252486,9606.ENSP00000254722,9606.ENSP00000308938,9606.ENSP00000345179,9606.ENSP00000346839,9606.ENSP00000355627,9606.ENSP00000366109,9606.ENSP00000370473,9606.ENSP00000389814	LBP,C5,VTN,GPLD1,HRG,APOE,SERPINF1,PLG,APOD,FN1,AGT,ANXA1,IGFBP3,ADIPOQ
GO:0060249	Anatomical structure homeostasis	8	296	0.79	0.54	0.0053	9606.ENSP00000231751,9606.ENSP00000261267,9606.ENSP00000263598,9606.ENSP00000291009,9606.ENSP00000308938,9606.ENSP00000360522,9606.ENSP00000440066,9606.ENSP00000450540	LTF,LYZ,LCN1,PIP,PLG,RBP4,JCHAIN,SERPINA3
GO:0051093	Negative regulation of developmental process	14	933	0.53	0.46	0.0056	9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000252486,9606.ENSP00000254722,9606.ENSP00000255030,9606.ENSP00000255040,9606.ENSP00000273784,9606.ENSP00000292609,9606.ENSP00000308541,9606.ENSP00000355627,9606.ENSP00000360522,9606.ENSP00000363770,9606.ENSP00000366109,9606.ENSP00000389814	LTF,HRG,APOE,SERPINF1,CRP,APCS,AHSG,PGLYRP2,F2,AGT,RBP4,C1QC,ANXA1,ADIPOQ
GO:1901564	Organonitrogen compound metabolic process	39	4981	0.25	0.35	0.0056	9606.ENSP00000181383,9606.ENSP00000222381,9606.ENSP00000222482,9606.ENSP00000230036,9606.ENSP00000231751,9606.ENSP00000241052,9606.ENSP00000252486,9606.ENSP00000261714,9606.ENSP00000263598,9606.ENSP00000264381,9606.ENSP00000264690,9606.ENSP00000265132,9606.ENSP00000265983,9606.ENSP00000266041,9606.ENSP00000273283,9606.ENSP00000277903,9606.ENSP00000291009,9606.ENSP00000291744,9606.ENSP00000292609,9606.ENSP00000296280,9606.ENSP00000299367,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000308938,9606.ENSP00000315130,9606.ENSP00000346839,9606.ENSP00000350425,9606.ENSP00000351190,9606.ENSP00000357156,9606.ENSP00000362924,9606.ENSP00000363079,9606.ENSP00000365081,9606.ENSP00000366109,9606.ENSP00000370473,9606.ENSP00000378131,9606.ENSP00000385035,9606.ENSP00000415769,9606.ENSP00000416561,9606.ENSP00000465356	CPB2,PON1,CPA4,GPLD1,LTF,CAT,APOE,BLMH,LCN1,BCHE,KLKB1,AMBP,HPX,ITIH4,ITIH1,HABP2,PIP,FCN2,PGLYRP2,MASP1,C2,FGB,F2,PLG,CLU,FN1,APOA4,ITIH2,CD5L,GSN,MBL2,APOM,ANXA1,IGFBP3,CFI,C1S,ITIH3,CFB,APOC1
GO:0010942	Positive regulation of cell death	11	590	0.63	0.49	0.0057	9606.ENSP00000230036,9606.ENSP00000232003,9606.ENSP00000251595,9606.ENSP00000252486,9606.ENSP00000315130,9606.ENSP00000355627,9606.ENSP00000362924,9606.ENSP00000366109,9606.ENSP00000370473,9606.ENSP00000389814,9606.ENSP00000493985	GPLD1,HRG,HBA2,APOE,CLU,AGT,GSN,ANXA1,IGFBP3,ADIPOQ,KNG1
GO:0031099	Regeneration	6	154	0.95	0.57	0.0066	9606.ENSP00000181383,9606.ENSP00000226218,9606.ENSP00000308938,9606.ENSP00000345179,9606.ENSP00000350425,9606.ENSP00000366109	CPB2,VTN,PLG,APOD,APOA4,ANXA1
GO:0019538	Protein metabolic process	33	3910	0.28	0.35	0.0068	9606.ENSP00000181383,9606.ENSP00000222482,9606.ENSP00000230036,9606.ENSP00000231751,9606.ENSP00000241052,9606.ENSP00000252486,9606.ENSP00000261714,9606.ENSP00000263598,9606.ENSP00000264381,9606.ENSP00000264690,9606.ENSP00000265132,9606.ENSP00000265983,9606.ENSP00000277903,9606.ENSP00000291009,9606.ENSP00000291744,9606.ENSP00000296280,9606.ENSP00000299367,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000308938,9606.ENSP00000315130,9606.ENSP00000346839,9606.ENSP00000350425,9606.ENSP00000357156,9606.ENSP00000362924,9606.ENSP00000363079,9606.ENSP00000365081,9606.ENSP00000366109,9606.ENSP00000370473,9606.ENSP00000378131,9606.ENSP00000385035,9606.ENSP00000416561,9606.ENSP00000465356	CPB2,CPA4,GPLD1,LTF,CAT,APOE,BLMH,LCN1,BCHE,KLKB1,AMBP,HPX,HABP2,PIP,FCN2,MASP1,C2,FGB,F2,PLG,CLU,FN1,APOA4,CD5L,GSN,MBL2,APOM,ANXA1,IGFBP3,CFI,C1S,CFB,APOC1
GO:0050829	Defense response to Gram-negative bacterium	5	97	1.07	0.57	0.0076	9606.ENSP00000217407,9606.ENSP00000231751,9606.ENSP00000261267,9606.ENSP00000291744,9606.ENSP00000308541	LBP,LTF,LYZ,FCN2,F2
GO:0051240	Positive regulation of multicellular organismal process	18	1505	0.43	0.4	0.0081	9606.ENSP00000181383,9606.ENSP00000217407,9606.ENSP00000223642,9606.ENSP00000226218,9606.ENSP00000230036,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000252486,9606.ENSP00000254722,9606.ENSP00000266718,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000308938,9606.ENSP00000315130,9606.ENSP00000346839,9606.ENSP00000355627,9606.ENSP00000366109,9606.ENSP00000389814	CPB2,LBP,C5,VTN,GPLD1,LTF,HRG,APOE,SERPINF1,LUM,FGB,F2,PLG,CLU,FN1,AGT,ANXA1,ADIPOQ
GO:0001894	Tissue homeostasis	7	238	0.82	0.51	0.0089	9606.ENSP00000231751,9606.ENSP00000261267,9606.ENSP00000263598,9606.ENSP00000291009,9606.ENSP00000360522,9606.ENSP00000440066,9606.ENSP00000450540	LTF,LYZ,LCN1,PIP,RBP4,JCHAIN,SERPINA3
GO:0042127	Regulation of cell population proliferation	19	1669	0.41	0.39	0.0094	9606.ENSP00000181383,9606.ENSP00000230036,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000252486,9606.ENSP00000254722,9606.ENSP00000255030,9606.ENSP00000264381,9606.ENSP00000308541,9606.ENSP00000308938,9606.ENSP00000315130,9606.ENSP00000345179,9606.ENSP00000346839,9606.ENSP00000355627,9606.ENSP00000360522,9606.ENSP00000360687,9606.ENSP00000366109,9606.ENSP00000370473,9606.ENSP00000389814	CPB2,GPLD1,LTF,HRG,APOE,SERPINF1,CRP,BCHE,F2,PLG,CLU,APOD,FN1,AGT,RBP4,PTGDS,ANXA1,IGFBP3,ADIPOQ
GO:0080090	Regulation of primary metabolic process	43	5899	0.22	0.32	0.0095	9606.ENSP00000181383,9606.ENSP00000215727,9606.ENSP00000223642,9606.ENSP00000226218,9606.ENSP00000230036,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000241052,9606.ENSP00000252486,9606.ENSP00000254722,9606.ENSP00000255040,9606.ENSP00000263598,9606.ENSP00000263946,9606.ENSP00000264690,9606.ENSP00000265132,9606.ENSP00000265983,9606.ENSP00000266041,9606.ENSP00000266718,9606.ENSP00000273283,9606.ENSP00000273784,9606.ENSP00000308541,9606.ENSP00000315130,9606.ENSP00000329374,9606.ENSP00000333203,9606.ENSP00000342850,9606.ENSP00000343445,9606.ENSP00000345179,9606.ENSP00000346839,9606.ENSP00000350425,9606.ENSP00000351190,9606.ENSP00000355627,9606.ENSP00000356037,9606.ENSP00000362924,9606.ENSP00000366109,9606.ENSP00000370473,9606.ENSP00000377783,9606.ENSP00000389814,9606.ENSP00000396688,9606.ENSP00000415769,9606.ENSP00000415941,9606.ENSP00000450540,9606.ENSP00000465356,9606.ENSP00000493985	CPB2,SERPIND1,C5,VTN,GPLD1,LTF,HRG,CAT,APOE,SERPINF1,APCS,LCN1,PKP1,KLKB1,AMBP,HPX,ITIH4,LUM,ITIH1,AHSG,F2,CLU,SERPINA7,SERPINA5,SERPINA6,SERPINB4,APOD,FN1,APOA4,ITIH2,AGT,C4BPA,GSN,ANXA1,IGFBP3,PROS1,ADIPOQ,C4A,ITIH3,C4B,SERPINA3,APOC1,KNG1
GO:0002762	Negative regulation of myeloid leukocyte differentiation	4	53	1.23	0.57	0.0096	9606.ENSP00000231751,9606.ENSP00000255040,9606.ENSP00000363770,9606.ENSP00000389814	LTF,APCS,C1QC,ADIPOQ
GO:0006826	Iron ion transport	4	53	1.23	0.57	0.0096	9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000264613,9606.ENSP00000265983	LTF,HRG,CP,HPX
GO:0034445	Negative regulation of plasma lipoprotein oxidation	2	2	2.35	0.62	0.0096	9606.ENSP00000350425,9606.ENSP00000365081	APOA4,APOM
GO:0048662	Negative regulation of smooth muscle cell proliferation	4	53	1.23	0.57	0.0096	9606.ENSP00000252486,9606.ENSP00000345179,9606.ENSP00000370473,9606.ENSP00000389814	APOE,APOD,IGFBP3,ADIPOQ
GO:1902998	Positive regulation of neurofibrillary tangle assembly	2	2	2.35	0.62	0.0096	9606.ENSP00000252486,9606.ENSP00000315130	APOE,CLU
GO:0010628	Positive regulation of gene expression	15	1146	0.47	0.39	0.0123	9606.ENSP00000217407,9606.ENSP00000223642,9606.ENSP00000255030,9606.ENSP00000263946,9606.ENSP00000264690,9606.ENSP00000265983,9606.ENSP00000266718,9606.ENSP00000291009,9606.ENSP00000315130,9606.ENSP00000346839,9606.ENSP00000355627,9606.ENSP00000360522,9606.ENSP00000362924,9606.ENSP00000366109,9606.ENSP00000389814	LBP,C5,CRP,PKP1,KLKB1,HPX,LUM,PIP,CLU,FN1,AGT,RBP4,GSN,ANXA1,ADIPOQ
GO:0031638	Zymogen activation	4	59	1.19	0.53	0.0138	9606.ENSP00000264690,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000357156	KLKB1,FGB,F2,CD5L
GO:0030203	Glycosaminoglycan metabolic process	5	115	0.99	0.49	0.0151	9606.ENSP00000266041,9606.ENSP00000273283,9606.ENSP00000292609,9606.ENSP00000351190,9606.ENSP00000415769	ITIH4,ITIH1,PGLYRP2,ITIH2,ITIH3
GO:0034014	Response to triglyceride	2	3	2.18	0.56	0.0152	9606.ENSP00000230036,9606.ENSP00000350425	GPLD1,APOA4
GO:0034447	Very-low-density lipoprotein particle clearance	2	3	2.18	0.56	0.0152	9606.ENSP00000252486,9606.ENSP00000465356	APOE,APOC1
GO:0032928	Regulation of superoxide anion generation	3	23	1.47	0.54	0.0156	9606.ENSP00000255030,9606.ENSP00000265627,9606.ENSP00000355627	CRP,PON3,AGT
GO:0050777	Negative regulation of immune response	6	185	0.87	0.47	0.0156	9606.ENSP00000265132,9606.ENSP00000292609,9606.ENSP00000296280,9606.ENSP00000343445,9606.ENSP00000356037,9606.ENSP00000366109	AMBP,PGLYRP2,MASP1,SERPINB4,C4BPA,ANXA1
GO:0002833	Positive regulation of response to biotic stimulus	6	187	0.86	0.46	0.0163	9606.ENSP00000217407,9606.ENSP00000232003,9606.ENSP00000265983,9606.ENSP00000291744,9606.ENSP00000296280,9606.ENSP00000363079	LBP,HRG,HPX,FCN2,MASP1,MBL2
GO:0008203	Cholesterol metabolic process	5	119	0.98	0.48	0.0170	9606.ENSP00000222381,9606.ENSP00000241052,9606.ENSP00000252486,9606.ENSP00000350425,9606.ENSP00000465356	PON1,CAT,APOE,APOA4,APOC1
GO:0034143	Regulation of toll-like receptor 4 signaling pathway	3	24	1.45	0.52	0.0172	9606.ENSP00000217407,9606.ENSP00000231751,9606.ENSP00000253354	LBP,LTF,BPIFB1
GO:0014910	Regulation of smooth muscle cell migration	4	65	1.14	0.49	0.0186	9606.ENSP00000226218,9606.ENSP00000355627,9606.ENSP00000370473,9606.ENSP00000389814	VTN,AGT,IGFBP3,ADIPOQ
GO:0042744	Hydrogen peroxide catabolic process	3	25	1.43	0.51	0.0190	9606.ENSP00000241052,9606.ENSP00000251595,9606.ENSP00000350425	CAT,HBA2,APOA4
GO:0098581	Detection of external biotic stimulus	3	25	1.43	0.51	0.0190	9606.ENSP00000217407,9606.ENSP00000292609,9606.ENSP00000415941	LBP,PGLYRP2,C4B
GO:0002698	Negative regulation of immune effector process	5	123	0.96	0.46	0.0192	9606.ENSP00000292609,9606.ENSP00000296280,9606.ENSP00000343445,9606.ENSP00000356037,9606.ENSP00000366109	PGLYRP2,MASP1,SERPINB4,C4BPA,ANXA1
GO:0042157	Lipoprotein metabolic process	5	123	0.96	0.46	0.0192	9606.ENSP00000230036,9606.ENSP00000252486,9606.ENSP00000350425,9606.ENSP00000365081,9606.ENSP00000465356	GPLD1,APOE,APOA4,APOM,APOC1
GO:0048523	Negative regulation of cellular process	36	4736	0.24	0.29	0.0207	9606.ENSP00000181383,9606.ENSP00000223642,9606.ENSP00000230036,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000241052,9606.ENSP00000252486,9606.ENSP00000253354,9606.ENSP00000254722,9606.ENSP00000255030,9606.ENSP00000255040,9606.ENSP00000263946,9606.ENSP00000264381,9606.ENSP00000265132,9606.ENSP00000265627,9606.ENSP00000273784,9606.ENSP00000291009,9606.ENSP00000292609,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000308938,9606.ENSP00000315130,9606.ENSP00000343445,9606.ENSP00000345179,9606.ENSP00000350425,9606.ENSP00000355627,9606.ENSP00000360522,9606.ENSP00000360687,9606.ENSP00000362924,9606.ENSP00000363770,9606.ENSP00000365081,9606.ENSP00000366109,9606.ENSP00000370473,9606.ENSP00000389814,9606.ENSP00000465356,9606.ENSP00000493985	CPB2,C5,GPLD1,LTF,HRG,CAT,APOE,BPIFB1,SERPINF1,CRP,APCS,PKP1,BCHE,AMBP,PON3,AHSG,PIP,PGLYRP2,FGB,F2,PLG,CLU,SERPINB4,APOD,APOA4,AGT,RBP4,PTGDS,GSN,C1QC,APOM,ANXA1,IGFBP3,ADIPOQ,APOC1,KNG1
GO:0010873	Positive regulation of cholesterol esterification	2	4	2.05	0.52	0.0211	9606.ENSP00000350425,9606.ENSP00000465356	APOA4,APOC1
GO:0051919	Positive regulation of fibrinolysis	2	4	2.05	0.52	0.0211	9606.ENSP00000264690,9606.ENSP00000308938	KLKB1,PLG
GO:1905908	Positive regulation of amyloid fibril formation	2	4	2.05	0.52	0.0211	9606.ENSP00000252486,9606.ENSP00000315130	APOE,CLU
GO:0033993	Response to lipid	12	827	0.52	0.37	0.0218	9606.ENSP00000217407,9606.ENSP00000222381,9606.ENSP00000230036,9606.ENSP00000241052,9606.ENSP00000254722,9606.ENSP00000264381,9606.ENSP00000350425,9606.ENSP00000355627,9606.ENSP00000360522,9606.ENSP00000360687,9606.ENSP00000366109,9606.ENSP00000389814	LBP,PON1,GPLD1,CAT,SERPINF1,BCHE,APOA4,AGT,RBP4,PTGDS,ANXA1,ADIPOQ
GO:0051171	Regulation of nitrogen compound metabolic process	41	5734	0.21	0.28	0.0218	9606.ENSP00000181383,9606.ENSP00000215727,9606.ENSP00000223642,9606.ENSP00000226218,9606.ENSP00000230036,9606.ENSP00000231751,9606.ENSP00000232003,9606.ENSP00000241052,9606.ENSP00000252486,9606.ENSP00000254722,9606.ENSP00000255040,9606.ENSP00000263598,9606.ENSP00000263946,9606.ENSP00000264690,9606.ENSP00000265132,9606.ENSP00000265983,9606.ENSP00000266041,9606.ENSP00000266718,9606.ENSP00000273283,9606.ENSP00000273784,9606.ENSP00000308541,9606.ENSP00000315130,9606.ENSP00000329374,9606.ENSP00000333203,9606.ENSP00000342850,9606.ENSP00000343445,9606.ENSP00000345179,9606.ENSP00000346839,9606.ENSP00000351190,9606.ENSP00000355627,9606.ENSP00000356037,9606.ENSP00000362924,9606.ENSP00000370473,9606.ENSP00000377783,9606.ENSP00000389814,9606.ENSP00000396688,9606.ENSP00000415769,9606.ENSP00000415941,9606.ENSP00000450540,9606.ENSP00000465356,9606.ENSP00000493985	CPB2,SERPIND1,C5,VTN,GPLD1,LTF,HRG,CAT,APOE,SERPINF1,APCS,LCN1,PKP1,KLKB1,AMBP,HPX,ITIH4,LUM,ITIH1,AHSG,F2,CLU,SERPINA7,SERPINA5,SERPINA6,SERPINB4,APOD,FN1,ITIH2,AGT,C4BPA,GSN,IGFBP3,PROS1,ADIPOQ,C4A,ITIH3,C4B,SERPINA3,APOC1,KNG1
GO:0001906	Cell killing	5	129	0.94	0.44	0.0227	9606.ENSP00000231751,9606.ENSP00000261267,9606.ENSP00000263408,9606.ENSP00000308541,9606.ENSP00000493985	LTF,LYZ,C9,F2,KNG1
GO:0030336	Negative regulation of cell migration	7	288	0.74	0.41	0.0232	9606.ENSP00000223642,9606.ENSP00000232003,9606.ENSP00000252486,9606.ENSP00000254722,9606.ENSP00000345179,9606.ENSP00000370473,9606.ENSP00000389814	C5,HRG,APOE,SERPINF1,APOD,IGFBP3,ADIPOQ
GO:0002227	Innate immune response in mucosa	3	28	1.38	0.48	0.0242	9606.ENSP00000231751,9606.ENSP00000253354,9606.ENSP00000350425	LTF,BPIFB1,APOA4
GO:0003331	Positive regulation of extracellular matrix constituent secretion	2	5	1.96	0.48	0.0281	9606.ENSP00000181383,9606.ENSP00000355627	CPB2,AGT
GO:0017038	Protein import	2	5	1.96	0.48	0.0281	9606.ENSP00000252486,9606.ENSP00000315130	APOE,CLU
GO:0034382	Chylomicron remnant clearance	2	5	1.96	0.48	0.0281	9606.ENSP00000252486,9606.ENSP00000465356	APOE,APOC1
GO:0045940	Positive regulation of steroid metabolic process	3	30	1.35	0.46	0.0284	9606.ENSP00000252486,9606.ENSP00000350425,9606.ENSP00000465356	APOE,APOA4,APOC1
GO:0043065	Positive regulation of apoptotic process	9	507	0.6	0.36	0.0305	9606.ENSP00000230036,9606.ENSP00000232003,9606.ENSP00000315130,9606.ENSP00000355627,9606.ENSP00000362924,9606.ENSP00000366109,9606.ENSP00000370473,9606.ENSP00000389814,9606.ENSP00000493985	GPLD1,HRG,CLU,AGT,GSN,ANXA1,IGFBP3,ADIPOQ,KNG1
GO:0010743	Regulation of macrophage derived foam cell differentiation	3	31	1.34	0.45	0.0306	9606.ENSP00000255030,9606.ENSP00000355627,9606.ENSP00000389814	CRP,AGT,ADIPOQ
GO:0010810	Regulation of cell-substrate adhesion	6	217	0.8	0.39	0.0307	9606.ENSP00000226218,9606.ENSP00000232003,9606.ENSP00000306099,9606.ENSP00000308938,9606.ENSP00000345179,9606.ENSP00000346839	VTN,HRG,FGB,PLG,APOD,FN1
GO:0097746	Blood vessel diameter maintenance	5	140	0.91	0.41	0.0307	9606.ENSP00000252486,9606.ENSP00000255030,9606.ENSP00000306099,9606.ENSP00000355627,9606.ENSP00000493985	APOE,CRP,FGB,AGT,KNG1
GO:0048660	Regulation of smooth muscle cell proliferation	5	142	0.9	0.4	0.0321	9606.ENSP00000252486,9606.ENSP00000345179,9606.ENSP00000355627,9606.ENSP00000370473,9606.ENSP00000389814	APOE,APOD,AGT,IGFBP3,ADIPOQ
GO:0014068	Positive regulation of phosphatidylinositol 3-kinase signaling	4	79	1.06	0.42	0.0327	9606.ENSP00000241052,9606.ENSP00000308541,9606.ENSP00000346839,9606.ENSP00000355627	CAT,F2,FN1,AGT
GO:0045089	Positive regulation of innate immune response	5	144	0.9	0.4	0.0337	9606.ENSP00000217407,9606.ENSP00000265983,9606.ENSP00000291744,9606.ENSP00000296280,9606.ENSP00000363079	LBP,HPX,FCN2,MASP1,MBL2
GO:0051384	Response to glucocorticoid	5	144	0.9	0.4	0.0337	9606.ENSP00000254722,9606.ENSP00000264381,9606.ENSP00000360687,9606.ENSP00000366109,9606.ENSP00000389814	SERPINF1,BCHE,PTGDS,ANXA1,ADIPOQ
GO:0062013	Positive regulation of small molecule metabolic process	5	147	0.89	0.39	0.0360	9606.ENSP00000230036,9606.ENSP00000252486,9606.ENSP00000350425,9606.ENSP00000366109,9606.ENSP00000389814	GPLD1,APOE,APOA4,ANXA1,ADIPOQ
GO:0034284	Response to monosaccharide	5	149	0.88	0.38	0.0380	9606.ENSP00000181383,9606.ENSP00000230036,9606.ENSP00000241052,9606.ENSP00000254722,9606.ENSP00000389814	CPB2,GPLD1,CAT,SERPINF1,ADIPOQ
GO:0010035	Response to inorganic substance	9	532	0.58	0.34	0.0394	9606.ENSP00000222381,9606.ENSP00000230036,9606.ENSP00000241052,9606.ENSP00000251595,9606.ENSP00000254722,9606.ENSP00000306099,9606.ENSP00000350425,9606.ENSP00000357695,9606.ENSP00000366109	PON1,GPLD1,CAT,HBA2,SERPINF1,FGB,APOA4,S100A16,ANXA1
GO:0010629	Negative regulation of gene expression	12	899	0.48	0.32	0.0395	9606.ENSP00000181383,9606.ENSP00000217407,9606.ENSP00000231751,9606.ENSP00000252486,9606.ENSP00000254722,9606.ENSP00000292609,9606.ENSP00000308541,9606.ENSP00000345179,9606.ENSP00000346839,9606.ENSP00000355627,9606.ENSP00000366109,9606.ENSP00000389814	CPB2,LBP,LTF,APOE,SERPINF1,PGLYRP2,F2,APOD,FN1,AGT,ANXA1,ADIPOQ
GO:0048878	Chemical homeostasis	12	904	0.48	0.31	0.0413	9606.ENSP00000181383,9606.ENSP00000231751,9606.ENSP00000252486,9606.ENSP00000254722,9606.ENSP00000264613,9606.ENSP00000265983,9606.ENSP00000308541,9606.ENSP00000350425,9606.ENSP00000355627,9606.ENSP00000360522,9606.ENSP00000365081,9606.ENSP00000389814	CPB2,LTF,APOE,SERPINF1,CP,HPX,F2,APOA4,AGT,RBP4,APOM,ADIPOQ
GO:0014012	Peripheral nervous system axon regeneration	2	7	1.81	0.42	0.0421	9606.ENSP00000345179,9606.ENSP00000350425	APOD,APOA4
GO:0032677	Regulation of interleukin-8 production	4	86	1.02	0.39	0.0421	9606.ENSP00000217407,9606.ENSP00000255030,9606.ENSP00000366109,9606.ENSP00000389814	LBP,CRP,ANXA1,ADIPOQ
GO:0034384	High-density lipoprotein particle clearance	2	7	1.81	0.42	0.0421	9606.ENSP00000252486,9606.ENSP00000365081	APOE,APOM
GO:0045650	Negative regulation of macrophage differentiation	2	7	1.81	0.42	0.0421	9606.ENSP00000363770,9606.ENSP00000389814	C1QC,ADIPOQ
GO:0046889	Positive regulation of lipid biosynthetic process	4	86	1.02	0.39	0.0421	9606.ENSP00000230036,9606.ENSP00000252486,9606.ENSP00000350425,9606.ENSP00000366109	GPLD1,APOE,APOA4,ANXA1
GO:0060267	Positive regulation of respiratory burst	2	7	1.81	0.42	0.0421	9606.ENSP00000217407,9606.ENSP00000440066	LBP,JCHAIN
GO:0042221	Response to chemical	31	4010	0.24	0.26	0.0436	9606.ENSP00000181383,9606.ENSP00000215727,9606.ENSP00000217407,9606.ENSP00000222381,9606.ENSP00000223642,9606.ENSP00000230036,9606.ENSP00000232003,9606.ENSP00000241052,9606.ENSP00000251595,9606.ENSP00000252486,9606.ENSP00000254722,9606.ENSP00000261714,9606.ENSP00000264381,9606.ENSP00000265132,9606.ENSP00000265627,9606.ENSP00000265983,9606.ENSP00000266041,9606.ENSP00000291009,9606.ENSP00000306099,9606.ENSP00000315130,9606.ENSP00000345179,9606.ENSP00000350425,9606.ENSP00000355627,9606.ENSP00000357695,9606.ENSP00000360522,9606.ENSP00000360687,9606.ENSP00000362924,9606.ENSP00000365081,9606.ENSP00000366109,9606.ENSP00000389814,9606.ENSP00000415941	CPB2,SERPIND1,LBP,PON1,C5,GPLD1,HRG,CAT,HBA2,APOE,SERPINF1,BLMH,BCHE,AMBP,PON3,HPX,ITIH4,PIP,FGB,CLU,APOD,APOA4,AGT,S100A16,RBP4,PTGDS,GSN,APOM,ANXA1,ADIPOQ,C4B
GO:0062012	Regulation of small molecule metabolic process	7	330	0.68	0.34	0.0436	9606.ENSP00000230036,9606.ENSP00000252486,9606.ENSP00000350425,9606.ENSP00000366109,9606.ENSP00000370473,9606.ENSP00000389814,9606.ENSP00000465356	GPLD1,APOE,APOA4,ANXA1,IGFBP3,ADIPOQ,APOC1
GO:0044788	Modulation by host of viral process	3	37	1.26	0.4	0.0440	9606.ENSP00000231751,9606.ENSP00000252486,9606.ENSP00000255040	LTF,APOE,APCS
GO:0045923	Positive regulation of fatty acid metabolic process	3	37	1.26	0.4	0.0440	9606.ENSP00000350425,9606.ENSP00000366109,9606.ENSP00000389814	APOA4,ANXA1,ADIPOQ
GO:0060191	Regulation of lipase activity	4	88	1.01	0.38	0.0440	9606.ENSP00000350425,9606.ENSP00000355627,9606.ENSP00000366109,9606.ENSP00000465356	APOA4,AGT,ANXA1,APOC1
GO:0046883	Regulation of hormone secretion	6	239	0.75	0.35	0.0442	9606.ENSP00000230036,9606.ENSP00000306099,9606.ENSP00000355627,9606.ENSP00000360522,9606.ENSP00000366109,9606.ENSP00000389814	GPLD1,FGB,AGT,RBP4,ANXA1,ADIPOQ
GO:0043170	Macromolecule metabolic process	40	5781	0.19	0.25	0.0460	9606.ENSP00000181383,9606.ENSP00000222482,9606.ENSP00000230036,9606.ENSP00000231751,9606.ENSP00000241052,9606.ENSP00000252486,9606.ENSP00000261714,9606.ENSP00000263598,9606.ENSP00000264381,9606.ENSP00000264690,9606.ENSP00000265132,9606.ENSP00000265983,9606.ENSP00000266041,9606.ENSP00000273283,9606.ENSP00000277903,9606.ENSP00000291009,9606.ENSP00000291744,9606.ENSP00000292609,9606.ENSP00000296280,9606.ENSP00000299367,9606.ENSP00000306099,9606.ENSP00000308541,9606.ENSP00000308938,9606.ENSP00000315130,9606.ENSP00000346839,9606.ENSP00000350425,9606.ENSP00000351190,9606.ENSP00000357156,9606.ENSP00000360687,9606.ENSP00000362924,9606.ENSP00000363079,9606.ENSP00000365081,9606.ENSP00000366109,9606.ENSP00000370473,9606.ENSP00000378131,9606.ENSP00000385035,9606.ENSP00000389814,9606.ENSP00000415769,9606.ENSP00000416561,9606.ENSP00000465356	CPB2,CPA4,GPLD1,LTF,CAT,APOE,BLMH,LCN1,BCHE,KLKB1,AMBP,HPX,ITIH4,ITIH1,HABP2,PIP,FCN2,PGLYRP2,MASP1,C2,FGB,F2,PLG,CLU,FN1,APOA4,ITIH2,CD5L,PTGDS,GSN,MBL2,APOM,ANXA1,IGFBP3,CFI,C1S,ADIPOQ,ITIH3,CFB,APOC1
GO:0043535	Regulation of blood vessel endothelial cell migration	4	90	1.0	0.37	0.0464	9606.ENSP00000232003,9606.ENSP00000252486,9606.ENSP00000308938,9606.ENSP00000366109	HRG,APOE,PLG,ANXA1