CDKN1C CDKN1C CDKN1C E2F1 TP53 TP53 TP53 TP53 ENST00000380725 ENST00000414822 ENST00000440480 ENST00000343380 ENST00000269305 ENST00000420246 ENST00000445888 ENST00000504937 (∆) IDENTIFICATION CODE* Age Tumor cells Characterization CDKN1C E2F1 TP53 CDKN1C-002 CDKN1C-001 CDKN1C-003 E2F1-001 TP53-001 TP53-005 TP53-002 TP53-008 554 Adult >80% Cortical / Common T-LBL -3,625 4,214 0,31 -2,80 -4,60 -1,81 1,31 1,28 0,16 0,28 0,74 238 Adult >80% PreT / Immature T-LBL -2,766 -0,761 0,536 -2,66 -4,30 -4,76 0,46 0,49 -0,73 -0,53 0,81 408 Adult >80% Cortical / Common T-LBL -2,795 -0,434 0,028 -3,53 -2,15 -4,42 0,05 0,46 -1,01 -0,47 -0,01 192 Adult 90% Cortical / Common T-LBL -5,38 1,769 -0,78 -2,82 -3,29 -4,32 1,46 -0,71 1,17 -1,33 2,65 346 Adult 95% Cortical / Common T-LBL -4,473 2,78 -0,184 -2,41 -25,99 -2,00 2,05 -9,74 0,21 -3,80 3,26 460 Pediatric 70% Cortical / Common T-LBL -3,522 0,933 -0,395 -1,13 -22,38 -1,50 1,10 -2,10 0,45 -0,57 2,41 840 Pediatric >80% ProT / Immature T-LBL -3,988 1,104 0,659 -3,52 -2,69 -4,43 1,66 1,32 0,97 0,52 1,26 521 Pediatric 90% Cortical / Common T-LBL -5,95 -4,12 -3,40 1,68 0,66 2,65 1,10 -0,05 829 Adult — Immature T-LBL -3,023 -0,436 0,171 188 Adult — T-LBL -3,251 1,046 0,046 135 Adult — Medular / Common T-LBL -5,107 1,742 -0,295 080 Pediatric — Medular / Common T-LBL -3,21 0,029 -0,666 104 Pediatric — Cortical / Common T-LBL -4,975 1,015 1,773 038 Pediatric — T-LBL -0,682 1,257 0,522 101 Pediatric — T-LBL -3,736 1,704 -1,689 209 Pediatric — T-LBL -1,187 0,453 0,389 639 Pediatric 80% Medular / Common T-LBL -2,498 -0,479 0,07 001 Pediatric — ProT-PreT / Immature T-LBL -2,766 2,651 0,547 *Identification of the biological samples of the Biobank will be subjected to a coding process. Each sample is assigned an identification code. qrtRT-PCR Ex te n d ed c o h o rt Ex p lo ra to ry c o h o rt Supplementary Table 1. Characterization of the human sample collection in the exploratory cohort. Lymphomas were diagnosed (see Characterization column) according to World Health Organization Classification of Hematological Malignancies and recommendations from the European