REPISALUD es el REPositorio Institucional de SALUD del Instituto de Salud Carlos III (ISCIII) y sus Fundaciones, el Centro Nacional de Investigaciones Cardiovasculares (CNIC) y el Centro Nacional de Investigaciones Oncológicas (CNIO), en el que se recoge en un único archivo digital y de acceso libre, la producción científica y académica de estos centros de referencia en sus áreas.

Informes y estudios institucionales del ISCIII sobre COVID-19

Clinical, microbiological, and molecular characterization of pediatric invasive infections by Streptococcus pyogenes in Spain in a context of global outbreak 

In December 2022, an alert was published in the UK and other European countries reporting an unusual increase in the incidence of Streptococcus pyogenes infections. Our aim was to describe the clinical, microbiological, and molecular characteristics of group A Streptococcus invasive infections (iGA...

Characterization of a selective, iron-chelating antifungal compound that disrupts fungal metabolism and synergizes with fluconazole 

Fungal infections are a growing global health concern due to the limited number of available antifungal therapies as well as the emergence of fungi that are resistant to first-line antimicrobials, particularly azoles and echinocandins. Development of novel, selective antifungal therapies is challen...

Causal mediation for uncausally related mediators in the context of survival analysis 

Objective: The study of the potential intermediate effect of several variables on the association between an exposure and a time-to-event outcome is a question of interest in epidemiologic research. However, to our knowledge, no tools have been developed for the evaluation of multiple correlated me...

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