REPISALUD es el REPositorio Institucional de SALUD del Instituto de Salud Carlos III (ISCIII) y sus Fundaciones, el
Centro Nacional de Investigaciones Cardiovasculares (CNIC) y el Centro Nacional de Investigaciones Oncológicas (CNIO),
en el que se recoge en un único archivo digital y de acceso libre, la producción científica y académica de estos centros
de referencia en sus áreas.
Informes y estudios institucionales del ISCIII sobre COVID-19
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DNA methylation and cancer incidence: lymphatic-hematopoietic versus solid cancers in the Strong Heart Study.
Epigenetic alterations may contribute to early detection of cancer. We evaluated the association of blood DNA methylation with lymphatic-hematopoietic cancers and, for comparison, with solid cancers. We also evaluated the predictive ability of DNA methylation for lymphatic-hematopoietic cancers.
B...
Toll-Like Receptors in Acute Kidney Injury.
Acute kidney injury (AKI) is an important health problem, affecting 13.3 million individuals/year. It is associated with increased mortality, mainly in low- and middle-income countries, where renal replacement therapy is limited. Moreover, survivors show adverse long-term outcomes, including increa...
Pneumococcal Choline-Binding Proteins Involved in Virulence as Vaccine Candidates.
Streptococcus pneumoniae is a pathogen responsible for millions of deaths worldwide. Currently, the available vaccines for the prevention of S. pneumoniae infections are the 23-valent pneumococcal polysaccharide-based vaccine (PPV-23) and the pneumococcal conjugate vaccines (PCV10 and PCV13). These...