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Título
Estimating influenza vaccine effectiveness in Spain using sentinel surveillance data
Autor(es)
Jimenez-Jorge, Silvia ISCIII | Mateo-Ontañon, Salvador de ISCIII | Delgado-Sanz, Concepcion ISCIII | Pozo Sanchez, Francisco ISCIII | Casas Flecha, Inmaculada ISCIII | García Cenoz, Manuel | Castilla Catalán, Jesús | Rodriguez, C | Vega, T | Quinones, C | Martinez, E | Vanrell, J M | Gimenez, J | Castrillejo, D | Altzibar, Jone M | Carril, F | Ramos, J M | Serrano, M C | Martinez, A | Torner, N | Perez, E | Gallardo, V | Larrauri, Amparo ISCIII | Spanish Influenza Sentinel Surveillance System
Fecha de publicación
2015-07-16
Cita
Euro Surveill. 2015 Jul 16;20(28). pii: 21187.
Idioma
Inglés
Tipo de documento
journal article
Resumen
We aimed to estimate influenza vaccine effectiveness (VE) against laboratory-confirmed influenza during three influenza seasons (2010/11 to 2012/2013) in Spain using surveillance data and to compare the results with data obtained by the cycEVA study, the Spanish component of the Influenza Monitoring Vaccine Effectiveness (I-MOVE) network. We used the test-negative case–control design, with data from the Spanish Influenza Sentinel Surveillance System (SISS) or from the cycEVA study. Cases were laboratory-confirmed influenza patients with the predominant influenza virus of each season, and controls were those testing negative for any influenza virus. We calculated the overall and age-specific adjusted VE. Although the number of patients recorded in the SISS was three times higher than that in the cycEVA study, the quality of information for important variables, i.e. vaccination status and laboratory results, was high in both studies. Overall, the SISS and cycEVA influenza VE estimates were largely similar during the study period. For elderly patients (> 59 years), the SISS estimates were slightly lower than those of cycEVA, and estimates for children (0–14 years) were higher using SISS in two of the three seasons studied. Enhancing the SISS by collecting the date of influenza vaccination and reducing the percentage of patients with incomplete information would optimise the system to provide reliable annual influenza VE estimates to guide influenza vaccination policies.
MESH
Adolescent | Adult | Aged | Aged, 80 and over | Case-Control Studies | Child | Child, Preschool | Female | Humans | Infant | Infant, Newborn | Influenza A Virus, H1N1 Subtype | Influenza Vaccines | Influenza, Human | Male | Middle Aged | Outcome Assessment, Health Care | Spain | Vaccination | Young Adult | Sentinel Surveillance
Descripción
Published Erratum Euro Surveill. 2015 Jul 23;20(29):21190. PMID: 26227373
Versión en línea
DOI
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