Por favor, use este identificador para citar o enlazar este Item:http://hdl.handle.net/20.500.12105/6864
Título
Platelets as autonomous drones for hemostatic and immune surveillance
Autor(es)
Fecha de publicación
2017-07-18
Cita
J Exp Med. 2017; 214(8):2193
Idioma
Inglés
Tipo de documento
journal article
Resumen
Platelets participate in many important physiological processes, including hemostasis and immunity. However, despite their broad participation in these evolutionarily critical roles, the anucleate platelet is uniquely mammalian. In contrast with the large nucleated equivalents in lower vertebrates, we find that the design template for the evolutionary specialization of platelets shares remarkable similarities with human-engineered unmanned aerial vehicles in terms of overall autonomy, maneuverability, and expendability. Here, we review evidence illustrating how platelets are uniquely suited for surveillance and the manner in which they consequently provide various types of support to other cell types.
Versión en línea
DOI
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